Europe — EMA
Panodil (Paracetamol)
GNH USA supplies Panodil (Paracetamol), an analgesic/antipyretic for pain relief and fever reduction. Request a product
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What is Paracetamol?
Paracetamol, the active ingredient in Panodil, is an analgesic presented as a rectal suppository for rectal use. It treats mild to moderate pain and reduces fever in children and adults. GNH USA supplies Panodil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Panodil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Panodil (paracetamol) is used across several common pain‑related pathways and fever mechanisms.
- Headache: provides relief from mild to moderate tension‑type headaches. - Fever: lowers elevated body temperature in febrile illnesses. - Musculoskeletal pain: eases discomfort from muscle aches, back pain and minor joint strain. - Dental pain: reduces pain associated with toothache or dental procedures. - Post‑operative pain: helps manage mild pain after minor surgical procedures.
What are the side effects of Paracetamol?
Paracetamol is generally well‑tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea - Abdominal discomfort - Mild skin rash - Transient elevation of liver enzymes
Serious or Rare Side Effects: - Severe skin reactions such as Stevens‑Johnson syndrome - Acute liver failure, especially with overdose - Hypersensitivity anaphylaxis - Blood disorders (e.g., thrombocytopenia)
What precautions apply to Paracetamol?
When using Panodil, consider the following safety measures:
- Dose limitation: adhere to maximum daily amount recommended for age and weight. - Liver health: avoid use in patients with existing liver disease or chronic alcohol use. - Concomitant medications: review other products containing paracetamol to prevent accidental overdose. - Pregnancy and lactation: consult healthcare professional before use during pregnancy or while breastfeeding. - Storage: Store at below 25°C: keep in the original pack, protect from moisture.
What does Paracetamol interact with?
Paracetamol may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: may increase bleeding risk. - High‑dose ibuprofen or NSAIDs: combined use can raise liver toxicity risk.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: may increase metabolic clearance. - Alcohol: chronic intake can potentiate hepatotoxicity.
