Panodil (Paracetamol)

Paracetamol, the active ingredient in Panodil, is an Analgesic presented as a tablet for oral use. It is used to relieve mild to moderate pain and to reduce fever in adults and children. GNH USA supplies Panodil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol acts as an analgesic and antipyretic, addressing pain and fever pathways. - Pain: provides relief of mild to moderate pain such as headache, toothache, or muscle aches. - Fever: lowers elevated body temperature associated with infections or inflammatory conditions. - Post‑operative discomfort: helps manage discomfort after minor surgical procedures.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset or queasiness. - Skin rash: occasional mild erythema or itching. - Abdominal discomfort: transient stomach pain. - Elevated liver enzymes: mild, reversible changes in laboratory tests. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: acute liver injury, especially with overdose or chronic high‑dose use. - Blood disorders: agranulocytosis or thrombocytopenia. - Anaphylaxis: rare but potentially life‑threatening allergic reaction.

Paracetamol should be used with awareness of specific safety considerations. - Dosage limits: adhere to maximum daily dose to avoid liver toxicity. - Alcohol consumption: limit intake as combined use increases hepatic risk. - Pre‑existing liver disease: use only under medical supervision. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential interactions. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Paracetamol may interact with several medicines, requiring careful management.

Major Interactions (Avoid): - Alcohol: concurrent use heightens risk of liver injury. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Carbamazepine or phenytoin: enzyme inducers that can reduce paracetamol effectiveness.

Moderate Interactions (Monitor Closely): - Other hepatotoxic drugs: combined use may increase liver strain. - Isoniazid: may potentiate liver enzyme elevations. - High‑dose vitamin C: can alter paracetamol metabolism. - Certain antiviral agents: may affect plasma concentrations.