Panodil Extra (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Panodil Extra, is an analgesic/antipyretic presented as a combination tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children when appropriate.

GNH USA supplies Panodil Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panodil Extra combines paracetamol and caffeine to address pain‑related pathways and fever. It is commonly used for: - Headache: provides relief of tension‑type and migraine‑associated pain. - Dental pain: reduces discomfort after dental procedures. - Musculoskeletal pain: alleviates aches from strain, sprain or arthritis. - Fever: lowers elevated body temperature in acute infections. - Cold‑related discomfort: eases sinus pressure and headache associated with common colds.

Adverse reactions may occur with any medication.

Common Side Effects: - Nausea: mild stomach upset reported in some users. - Insomnia: difficulty sleeping due to caffeine content. - Gastric discomfort: mild abdominal pain or heartburn. - Headache: paradoxical headache in rare cases. - Rash: mild skin irritation or itching.

Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with excessive paracetamol intake. - Allergic reaction: hives, swelling, or anaphylaxis. - Blood disorders: rare cases of thrombocytopenia or neutropenia. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiovascular effects: palpitations or arrhythmia linked to caffeine.

When using Panodil Extra, consider the following safety measures: - Dose limitation: avoid exceeding the maximum daily paracetamol amount. - Liver health: assess hepatic function in patients with liver disease. - Caffeine sensitivity: monitor individuals prone to anxiety, insomnia or tachycardia. - Pregnancy and lactation: use only if clearly indicated and prescribed. - Drug interactions: review concomitant medications for potential synergy. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Panodil Extra may interact with several medicines.

Major Interactions (Avoid): - Warfarin: increased bleeding risk due to altered metabolism. - Isoniazid: heightened hepatotoxic potential. - Highly active antiretroviral therapy: may affect paracetamol clearance.

Moderate Interactions (Monitor Closely): - Other CNS stimulants: additive effects on heart rate and anxiety. - Diuretics: potential for reduced plasma volume affecting drug concentration. - Oral contraceptives: may increase paracetamol plasma levels. - Antiepileptic drugs: enzyme induction may lower analgesic efficacy.