Panadol Retard 8 Uur (Paracetamol)

Paracetamol, the active ingredient in Panadol Retard 8 Uur, is an analgesic presented as a prolonged‑release tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children over six years of age. GNH USA supplies Panadol Retard 8 Uur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Panadol Retard 8 Uur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panadol Retard 8 Uur contains paracetamol, an analgesic‑antipyretic that works on the central pain‑relief pathway.

- Headache: provides sustained relief of tension‑type and mild migraine headache. - Dental pain: reduces postoperative dental discomfort for up to eight hours. - Musculoskeletal pain: alleviates back, joint and muscle aches with prolonged effect. - Fever: lowers elevated body temperature in acute febrile states. - Menstrual cramps: eases dysmenorrhoea with extended symptom control.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be experienced. - Rash: occasional skin redness or itching. - Elevated liver enzymes: transient increase in laboratory values. - Headache: paradoxical headache in a minority of users.

Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: extremely rare allergic response. - Blood disorders: rare cases of thrombocytopenia or neutropenia.

When using Panadol Retard 8 Uur, consider the following safety measures:

- Liver function monitoring: assess hepatic health in patients with chronic liver disease. - Alcohol consumption: limit intake as alcohol can increase hepatotoxic risk. - Concomitant paracetamol: avoid using other paracetamol‑containing products to prevent overdose. - Pregnancy and lactation: use only if clearly indicated and prescribed by a healthcare professional. - Storage: Store below 25°C: keep in the original pack, protect from moisture.

Paracetamol may interact with several medicines; awareness helps prevent adverse events.

Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Isoniazid: can potentiate liver toxicity when combined with paracetamol.

Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine, phenytoin): may increase paracetamol metabolism, reducing efficacy. - Rifampicin: accelerates hepatic clearance, potentially lowering therapeutic effect. - HIV‑Mediated ​     ​  ​  ​  ​  ​  ​  ​  ​  ​  ​  ​