Panadol Plus Gladde Tablet (Paracetamol, Caffeine)

Paracetamol, the active ingredient in Panadol Plus Gladde, is an analgesic/antipyretic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children when combined with caffeine. GNH USA supplies Panadol Plus Gladde as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Panadol Plus Gladde as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panadol Plus Gladde combines paracetamol and caffeine to relieve pain and fever through central nervous system pathways.

- Headache: provides rapid relief of tension‑type and migraine‑associated pain. - Dental pain: reduces discomfort after dental procedures. - Musculoskeletal pain: eases aches from strains, sprains and back pain. - Fever: lowers elevated body temperature in acute infections. - Cold‑related discomfort: alleviates sinus pressure and headache associated with common colds.

Paracetamol/caffeine tablets are generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Insomnia: caffeine may cause difficulty falling asleep. - Gastro‑intestinal discomfort: mild abdominal pain or dyspepsia. - Headache: paradoxical headache in rare cases. - Sweating: occasional increased perspiration. - Dizziness: transient light‑headedness.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling or anaphylaxis. - Hepatotoxicity: liver injury with excessive dosing. - Blood disorders: thrombocytopenia or neutropenia. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Cardiovascular effects: palpitations or arrhythmia from caffeine. - Renal impairment: acute kidney injury in susceptible individuals.

When using Panadol Plus Gladde, consider the following safety measures.

- Dose limitation: do not exceed the maximum daily paracetamol amount recommended for adults. - Liver health: avoid use in patients with severe hepatic impairment or active liver disease. - Caffeine sensitivity: caution in individuals prone to insomnia, anxiety or tachycardia. - Pregnancy and lactation: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential additive effects. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Paracetamol/caffeine may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Warfarin: increased risk of bleeding due to altered metabolism. - High‑dose ibuprofen or other NSAIDs: heightened risk of liver and gastrointestinal toxicity.

Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol effectiveness. - Mono‑mono‑mono   ");