Panadol Nightpain (Diphenhydramine Hydrochloride, Paracetamol)

Diphenhydramine Hydrochloride, the active ingredient in Panadol Nightpain, is a first‑generation antihistamine combined with paracetamol presented as a tablet for oral use. It is used to relieve mild to moderate pain and to help with sleep when pain interferes with rest. GNH USA supplies Panadol Nightpain as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panadol Nightpain contains diphenhydramine and paracetamol, which act on pain‑related pathways and histamine receptors to provide relief and promote sleep. - Headache: Reduces pain intensity and helps the patient rest. - Muscular aches and pains: Alleviates discomfort associated with muscle strain. - Fever associated with pain: Lowers body temperature while easing pain. - Minor arthritic pain: Provides analgesic effect for mild joint discomfort. - Tension‑type headache: Relieves tension‑related head pain.

Side effects may vary in frequency and severity.

Common Side Effects: - Drowsiness: Feeling unusually sleepy or fatigued. - Dry mouth: Reduced salivation leading to a dry sensation. - Dizziness: Light‑headed feeling, especially when standing quickly. - Nausea: Mild stomach upset or queasiness. - Blurred vision: Temporary visual disturbance.

Serious or Rare Side Effects: - Severe allergic reaction: Rash, itching, swelling, or difficulty breathing. - Liver injury: Unexplained jaundice or dark urine. - Cardiac arrhythmia: Irregular heartbeat. - Hallucinations or confusion: Altered mental state. - Persistent vomiting: Inability to retain fluids.

When using Panadol Nightpain, consider the following safety measures: - Avoid alcohol: Increases sedation and liver load. - Liver disease: Use only under medical supervision. - Pregnancy and breastfeeding: Consult a healthcare professional before use. - Elderly patients: Start with the lowest effective dose and monitor for confusion. - Concomitant CNS depressants: May enhance drowsiness. - Store below 25°C: Keep in the original packaging, protect from moisture and direct sunlight.

Panadol Nightpain can interact with several medicines. Review these categories:

Major Interactions (Avoid): - Alcohol: Potentiates central nervous system depression and liver toxicity. - Strong CYP450 inhibitors: May increase paracetamol levels, raising risk of hepatotoxicity. - Monoamine oxidase inhibitors (MAOIs): Heightened anticholinergic effects.

Moderate Interactions (Monitor Closely): - Other sedatives or antihistamines: Additive drowsiness. - Warfarin: May enhance anticoagulant effect. - Antiepileptic drugs: May alter paracetamol metabolism.