Panadol Night (Diphenhydramine Hydrochloride, Paracetamol)

Diphenhydramine Hydrochloride, the active ingredient in Panadol Night, is an antihistamine combined with an analgesic presented as a tablet for oral use. It relieves occasional nighttime pain and helps with sleep.

GNH USA supplies Panadol Night as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panadol Night combines an analgesic and a sedating antihistamine to address pain that interferes with sleep. It is commonly used for: - Headache: reduces pain and promotes restfulness. - Minor musculoskeletal pain: eases aches and helps the user fall asleep. - Fever with discomfort: lowers temperature while providing nighttime relief. - Toothache: alleviates dental pain that disrupts sleep. - Menstrual cramps: lessens cramping pain and aids sleep onset.

Side effects may vary in frequency and severity.

Common Side Effects: - Drowsiness: feeling unusually sleepy. - Dry mouth: reduced salivation. - Dizziness: light‑headed sensation. - Blurred vision: temporary focus issues. - Constipation: reduced bowel movements. - Nausea: mild stomach upset.

Serious or Rare Side Effects: - Severe allergic reaction: rash, swelling, or breathing difficulty. - Liver injury: jaundice or dark urine. - Cardiac arrhythmia: irregular heartbeat. - Hallucinations or confusion: altered mental state. - Persistent vomiting: inability to keep fluids down. - Low blood pressure: dizziness on standing.

When using Panadol Night, consider the following safety measures: - Avoid alcohol: increases sedation and liver risk. - Do not operate machinery: drowsiness can impair coordination. - Monitor liver function: especially with chronic use or existing liver disease. - Use caution in the elderly: heightened sensitivity to sedative effects. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Panadol Night may interact with several medicines. Review the following categories:

Major Interactions (Avoid): - Alcohol: amplifies central nervous system depression and liver toxicity. - Other CNS depressants: combined sedation may be excessive. - Hepatotoxic drugs: increased risk of liver injury.

Moderate Interactions (Monitor Closely): - Anticoagulants: paracetamol can enhance anticoagulant effect. - Anticholinergic drugs: may worsen dry‑mouth and urinary retention. - MAO inhibitors: potential for heightened hypertensive response.