Europe — EMA
Panadol Extra Advance (Paracetamol, Caffeine)
Paracetamol, the active ingredient in Panadol Extra Advance, is an analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children when appropriate.
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Panadol Extra Advance, is an analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children when appropriate.
GNH USA supplies Panadol Extra Advance as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Panadol Extra Advance combines paracetamol and caffeine, acting on pain‑related pathways and fever mechanisms. - Headache: provides relief from tension‑type and occasional migraine headache. - Dental pain: reduces discomfort after dental procedures. - Musculoskeletal pain: eases aches from back strain, sprains and minor joint pain. - Fever: helps lower elevated body temperature associated with infection.
What are the side effects of Paracetamol, Caffeine?
Adverse reactions to Panadol Extra Advance are generally mild and reversible.
Common Side Effects: - Nausea: occasional stomach upset. - Insomnia: difficulty falling asleep, especially if taken later in the day. - Restlessness: mild feeling of unease. - Increased heart rate: slight tachycardia.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Liver injury: signs include jaundice, dark urine, or upper‑right abdominal pain. - Blood disorders: unexplained bruising or bleeding. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
What precautions apply to Paracetamol, Caffeine?
When using Panadol Extra Advance, consider the following safety measures: - Maximum daily dose: do not exceed the recommended total paracetamol amount from all sources. - Liver health: avoid use if you have active liver disease or elevated liver enzymes. - Alcohol consumption: limit intake as it may increase liver toxicity risk. - Pregnancy and breastfeeding: consult a healthcare professional before use. - Drug interactions: review all concurrent medications with a pharmacist. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol, Caffeine interact with?
Panadol Extra Advance may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: increased risk of bleeding. - Certain antiepileptics (e.g., carbamazepine, phenytoin): may reduce paracetamol effectiveness.
Moderate Interactions (Monitor Closely): - Other analgesics containing paracetamol: risk of accidental overdose. - Monoamine oxidase inhibitors (MAOIs): potential for heightened stimulant effects from caffeine. - Beta‑beta‑beta ").
