Europe — EMA
Panadol Extra (Paracetamol, Caffeine)
Paracetamol, the active ingredient in Panadol Extra, is an analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children.
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Panadol Extra, is an analgesic presented as a tablet for oral use. It treats mild to moderate pain and reduces fever in adults and children. Caffeine, the secondary ingredient, enhances the analgesic effect of paracetamol. GNH USA supplies Panadol Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Panadol Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Panadol Extra combines paracetamol and caffeine to relieve pain and reduce fever through central analgesic pathways.
- Headache: provides rapid relief of tension‑type and mild migraine pain. - Fever: lowers elevated body temperature in acute febrile episodes. - Musculoskeletal pain: eases discomfort from backache, muscle strains and minor joint pain. - Dental pain: alleviates pain following dental procedures or toothache. - Menstrual discomfort: reduces cramping and associated low‑grade fever.
What are the side effects of Paracetamol, Caffeine?
Paracetamol and caffeine are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be reported. - Insomnia: caffeine‑related difficulty falling asleep. - Gastro‑intestinal discomfort: occasional stomach irritation. - Headache: paradoxical headache in rare cases. - Dizziness: transient light‑headedness. - Rash: mild skin redness or itching.
Serious or Rare Side Effects: - Stevens‑Stevenson reaction: severe skin blistering and detachment. - Anaphylaxis: acute, life‑threatening allergic reaction. - Hepatotoxicity: liver injury with excessive dosing. - Blood disorders: thrombocytopenia or neutropenia. - Severe rash: toxic epidermal necrolysis. - Cardiac arrhythmias: irregular heartbeat linked to high caffeine intake.
What precautions apply to Paracetamol, Caffeine?
When using Panadol Extra, consider the following safety measures:
- Dose limitation: do not exceed the maximum daily amount of paracetamol. - Liver health: avoid use in patients with severe hepatic impairment. - Caffeine sensitivity: caution in individuals prone to insomnia or palpitations. - Pregnancy and lactation: consult a healthcare professional before use. - Drug interactions: review concomitant medications for potential conflicts. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol, Caffeine interact with?
Panadol Extra may interact with several medication classes. Review
Major Interactions (Avoid): - Warfarin: may increase bleeding risk. - Isoniazid: heightens risk of liver toxicity. - High‑dose vitamin A: combined hepatotoxic .
Moderate Moderate Interactions (Monitor Closely): - Antidepressants: may enhance serotonergic . - Antiepileptic . - The ": " """"""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""
