Europe — EMA
Panadol Extra (Paracetamol, Caffeine)
Paracetamol, the active ingredient in Panadol Extra, is an analgesic and antipyretic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children when combined with…
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What is Paracetamol, Caffeine?
Paracetamol, the active ingredient in Panadol Extra, is an analgesic and antipyretic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children when combined with caffeine. GNH USA supplies Panadol Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Panadol Extra as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol, Caffeine used for?
Panadol Extra combines paracetamol and caffeine to address pain‑related pathways and enhance analgesic effectiveness.
- Headache: provides relief from tension‑type and mild migraine headaches. - Fever: helps lower elevated body temperature associated with viral or bacterial infections. - Muscular pain: eases soreness and discomfort from minor muscle strains or over‑exertion. - Dental pain: reduces pain following dental procedures or toothache. - Menstrual discomfort: lessens cramping and associated lower‑back pain.
What are the side effects of Paracetamol, Caffeine?
Paracetamol/caffeine tablets are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild stomach upset may be reported. - Insomnia: caffeine can cause difficulty falling asleep. - Restlessness: occasional feeling of jitteriness. - Headache: paradoxical headache in rare cases. - Gastro‑intestinal discomfort: mild abdominal pain or indigestion.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Hepatotoxicity: liver injury with excessive dosing or pre‑existing liver disease. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylaxis: rapid onset of life‑threatening allergic response. - Blood disorders: unexplained bruising or bleeding.
What precautions apply to Paracetamol, Caffeine?
When using Panadol Extra, consider the following safety measures:
- Dose limitation: do not exceed the maximum daily amount of paracetamol. - Liver health: avoid use in patients with severe hepatic impairment. - Caffeine sensitivity: caution in individuals prone to anxiety or insomnia. - Drug interactions: review concomitant medications for potential additive effects. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol, Caffeine interact with?
Paracetamol and caffeine may interact with several medicines; monitoring is advised.
Major Interactions (Avoid): - Warfarin: increased risk of bleeding due to altered metabolism. - Carbamazepine: may reduce paracetamol effectiveness. - Mono‑mono ": """"""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""..



