Panadol Actifast (Paracetamol)

Paracetamol, the active ingredient in Panadol Actifast, is an analgesic presented as a 500 mg tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.

GNH USA supplies Panadol Actifast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Panadol Actifast contains paracetamol, an analgesic that acts on common pain‑related pathways. - Headache: provides relief from tension‑type and mild migraine pain. - Fever: lowers elevated body temperature associated with viral or bacterial infections. - Musculoskeletal pain: eases aches from back strain, minor sprains and everyday joint discomfort. - Dental pain: reduces discomfort following dental procedures or toothache. - Menstrual discomfort: helps alleviate mild dysmenorrhoeic cramps.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset may be reported. - Skin rash: occasional mild erythema or itching. - Elevated liver enzymes: transient increase detected in blood tests.

Serious or Rare Side Effects: - Hepatotoxicity: risk of liver injury with overdose or chronic high‑dose use. - Stevens‑Johnson syndrome: rare severe skin reaction. - Anaphylaxis: extremely rare allergic response requiring immediate medical attention. - Blood disorders: rare cases of thrombocytopenia or neutropenia.

When using Panadol Actifast, consider the following safety measures: - Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional. - Alcohol use: avoid concurrent heavy alcohol consumption as it may increase liver risk. - Pre‑existing liver disease: use only under medical supervision. - Drug interactions: review all concurrent medications with a pharmacist. - Pregnancy and lactation: consult a healthcare provider before use. Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Paracetamol may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Isoniazid: can raise risk of liver toxicity when combined with paracetamol.

Moderate Interactions (Monitor Closely): - Antiepileptics (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: may increase metabolism of paracetamol, lowering efficacy. - Oral contraceptives: may slightly increase hepatotoxic potential. - High‑dose vitamin C: can affect paracetamol metabolism. - Herbal supplements such as St St