Europe — EMA
Panadol Actifast (Paracetamol)
Paracetamol, the active ingredient in Panadol Actifast, is an analgesic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children.
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What is Paracetamol?
Paracetamol, the active ingredient in Panadol Actifast, is an analgesic presented as a tablet for oral use. It relieves mild to moderate pain and reduces fever in adults and children. GNH USA supplies Panadol Actifast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Panadol Actifast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Paracetamol used for?
Panadol Actifast contains paracetamol, an analgesic that acts on the body's pain‑relief pathways and fever response.
- Headache: provides relief from tension‑type and mild migraine headaches. - Fever: reduces elevated body temperature associated with viral or bacterial infections. - Musculoskeletal pain: eases discomfort from muscle aches, back pain, and minor joint strain. - Dental pain: alleviates pain following dental procedures or toothache. - Cold symptoms: helps control mild pain and fever that accompany common colds.
What are the side effects of Paracetamol?
Paracetamol is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: occasional mild stomach upset. - Skin rash: transient redness or itching. - Elevated liver enzymes: mild, reversible changes in liver function tests.
Serious or Rare Side Effects: - Hepatotoxicity: potential liver injury with excessive dosing. - Stevens‑Johnson syndrome: severe skin reaction, very rare. - Anaphylaxis: acute allergic response, extremely rare. - Blood disorders: rare cases of thrombocytopenia or neutropenia.
What precautions apply to Paracetamol?
When using Panadol Actifast, consider the following safety measures:
- Dose limits: adhere to maximum daily paracetamol intake recommended for age and weight. - Liver health: avoid use in patients with severe hepatic impairment or active liver disease. - Alcohol use: limit alcohol consumption as it may increase liver toxicity risk. - Concomitant medications: review other products containing paracetamol to prevent accidental overdose. - Pregnancy and lactation: consult a healthcare professional before use during pregnancy or while breastfeeding. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.
What does Paracetamol interact with?
Paracetamol may interact with several medicines, requiring attention to dosing and monitoring.
Major Interactions (Avoid): - Warfarin: may enhance anticoagulant effect and increase bleeding risk. - Isoniazid: can raise risk of liver toxicity when combined with paracetamol.
Moderate Interactions (Monitor Closely): - Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce paracetamol plasma levels. - Rifampicin: may increase metabolism of paracetamol, lowering its effectiveness. - Certain HIV‑M‑SMS ---
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