Europe — EMA
Palonosetron Seacross Pharmaceuticals
Palonosetron, the active ingredient in Palonosetron Seacross Pharmaceuticals, is a 5‑HT3 receptor antagonist presented as a 0.075 mg/2 ml solution for intravenous use.
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What is Palonosetron?
Palonosetron, the active ingredient in Palonosetron Seacross Pharmaceuticals, is a 5‑HT3 receptor antagonist presented as a 0.075 mg/2 ml solution for intravenous use. It is employed to prevent chemotherapy‑induced nausea and vomiting in adult cancer patients. GNH USA supplies Palonosetron Seacross Pharmaceuticals as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
GNH USA supplies Palonosetron Seacross Pharmaceuticals as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
What is Palonosetron used for?
Palonosetron is a selective 5‑HT3 receptor antagonist used in the management of nausea and vomiting related to specific therapeutic pathways.
- Chemotherapy‑induced nausea and vomiting (CINV): Provides effective prophylaxis for acute and delayed phases in adult patients receiving moderately to highly emetogenic chemotherapy. - Post‑operative nausea and vomiting (PONV): Reduces the incidence of nausea and vomiting after surgical procedures requiring general anesthesia. - Radiotherapy‑induced nausea and vomiting: Helps mitigate the nausea associated with radiation treatment of the abdomen or pelvis. - Antiemetic prophylaxis in patients receiving highly intense multimodal anti‑emetic regimens. - Adjunctive therapy for breakthrough nausea in patients already on a standard anti‑emetic protocol. - Support for patients under palliative care with refractory nausea that is not controlled by first‑line agents.
What are the side effects of Palonosetron?
Palonosetron is generally well‑tolerated, but adverse reactions can occur.
Common Side Effects: - Headache - Constipation - Fatigue - Dizziness - Injection site erythema - Diarrhoea Serious or Rare Side Effects: - QT‑interval prolongation - Severe hypersensitivity reactions (anaphylaxis, angio‑angelf ) - Serotonin syndrome - Cardiac arrhythmia - Pulmonary edema - Neuro‑muscular weakness
What precautions apply to Palonosetron?
Palonosetron should be administered
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