Europe — EMA
Palonosetron Kalceks
Palonosetron, the active ingredient in Palonosetron Kalceks, is a 5‑HT3 receptor antagonist presented as a 0.075 mg/2 ml solution for intravenous use.
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What is Palonosetron?
Palonosetron, the active ingredient in Palonosetron Kalceks, is a 5‑HT3 receptor antagonist presented as a 0.075 mg/2 ml solution for intravenous use. It is used to prevent nausea and vomiting associated with chemotherapy and postoperative settings in adult patients. GNH USA supplies Palonosetron Kalceks as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
GNH USA supplies Palonosetron Kalceks as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
What is Palonosetron used for?
Palonosetron Kalceks is a 5‑HT3 receptor antagonist indicated for several clinical situations involving nausea and vomiting.
- Chemotherapy‑induced nausea and vomiting (CINV): Provides prophylaxis against acute and delayed CINV in adult patients receiving moderately to high‑emetogenic chemotherapy. - Post‑operative nausea and vomiting (PONV): Reduces the incidence of nausea and vomiting after surgical procedures requiring general anesthesia. - Radiotherapy‑induced nausea and vomiting: Helps prevent the onset of nausea and vomiting during radiation treatment. - Antiemetic prophylaxis for patients receiving highly high dose stem cell transplant conditioning regimens.
What are the side effects of Palonosetron?
Palonosetron is generally well‑tolerated, but adverse reactions can occur.
Common Side Effects: - Headache - Constipation - Fatigue - Diarrhoea - Dizziness
Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - QT‑interval prolongation - Serotonin syndrome - Cardiac arrhythmias - Persistent severe constipation (obstruction).
What precautions apply to Palonosetron?
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