Paidofebril (Ibuprofen)

Ibuprofen, the active ingredient in Paidofebril, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a oral tablet for oral use. It treats pain, inflammation and fever in adults and children when appropriate.

GNH USA supplies Paidofebril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paidofebril is an NSAID that reduces inflammation and pain across several common conditions. - Rheumatoid arthritis: helps relieve joint pain and swelling, improving mobility. - Osteoarthritis: reduces pain associated with joint degeneration, aiding daily activities. - Acute musculoskeletal pain: eases pain from sprains, strains and minor injuries. - Dysmenorrhea: lessens menstrual cramps and associated discomfort. - Fever: lowers elevated body temperature in febrile states.

Adverse reactions to ibuprofen may vary in frequency and severity.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache: mild to moderate intensity. - Dizziness: transient episodes of light‑headedness. - Rash: mild skin redness or itching. - Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe allergic reactions: anaphylaxis, angioedema. - Liver injury: hepatitis or elevated transaminases. - Kidney impairment: acute renal failure or reduced function. - Cardiovascular events: increased risk of heart attack or stroke.

When using Paidofebril, consider the following safety measures: - Assess renal function: evaluate kidney health before initiating therapy. - Monitor gastrointestinal risk: avoid use in patients with active ulcers or a history of GI bleeding. - Check cardiovascular status: use cautiously in individuals with hypertension or heart disease. - Review concomitant medications: assess for potential drug interactions, especially anticoagulants. - Pregnancy and lactation: limit use to situations where benefits outweigh risks. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Ibuprofen can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding risk. - ACE inhibitors or ARBs: may reduce renal protective effects and increase kidney injury.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance diuretic‑induced electrolyte loss. - Lithium: ibuprofen can raise lithium serum levels. - Methotrexate: potential increase in methotrexate toxicity. - Corticosteroids: combined use raises ulcer risk.