Europe — EMA
Paduden (Ibuprofen)
Ibuprofen, the active ingredient in Paduden, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a oral tablet for systemic use.
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What is Ibuprofen?
Ibuprofen, the active ingredient in Paduden, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a oral tablet for systemic use. It relieves pain, reduces fever and decreases inflammation in adults and children when appropriate.
GNH USA supplies Paduden as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Ibuprofen used for?
Ibuprofen acts on inflammatory pathways to provide analgesic and antipyretic effects. - Mild to moderate pain: reduces pain intensity in conditions such as headache, dental pain, and musculoskeletal aches. - Fever: lowers elevated body temperature in febrile states. - Inflammatory disorders: diminishes swelling and discomfort in conditions like osteoarthritis and rheumatoid arthritis.
What are the side effects of Ibuprofen?
Adverse reactions may range from mild to severe and should be monitored during therapy.
Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache: mild to moderate intensity. - Dizziness or light‑headedness. - Rash or mild skin irritation. - Elevated blood pressure: transient increases.
Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe skin reactions such as Stevens‑Johnson syndrome. - Renal impairment or acute kidney injury. - Hepatotoxicity or elevated liver enzymes. - Anaphylaxis or severe allergic reactions.
What precautions apply to Ibuprofen?
When using Paduden, consider several safety measures to minimise risks. - Assess renal function: evaluate patients with pre‑existing kidney disease. - Monitor gastrointestinal health: avoid use in patients with active ulcers or a history of GI bleeding. - Evaluate cardiovascular risk: use cautiously in individuals with hypertension or heart disease. - Review concomitant medications: check for other NSAIDs or anticoagulants. - Pregnancy and breast‑feeding: consult the appropriate clinical guidelines for risk assessment. - Store at ambient temperature: keep the tablet in the original pack and protect from moisture.
What does Ibuprofen interact with?
Ibuprofen may interact with several medicines, altering efficacy or safety.
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