Paduden Express (Ibuprofen)

Ibuprofen, the active ingredient in Paduden Express, is a non‑steroidal anti‑inflammatory drug presented as a 200 mg tablet for oral use. It relieves pain, reduces fever and decreases inflammation in adults and children when appropriate. GNH USA supplies Paduden Express as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ibuprofen acts on inflammatory pathways to provide analgesic, antipyretic and anti‑inflammatory effects. - Mild to moderate pain: eases headache, dental pain, musculoskeletal aches and menstrual cramps. - Fever: lowers elevated body temperature in acute febrile states. - Inflammatory conditions: reduces swelling and discomfort in osteoarthritis and rheumatoid arthritis flares.

Adverse reactions may occur with ibuprofen use.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia or heartburn. - Headache or dizziness. - Mild skin rash or itching. - Elevated blood pressure.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding. - Severe allergic reactions such as anaphylaxis. - Hepatic or renal impairment. - Cardiovascular events including myocardial infarction or stroke.

When using Paduden Express, consider the following safety measures: - Assess renal function: patients with chronic kidney disease should be evaluated before use. - Monitor gastrointestinal risk: avoid in individuals with a history of ulcers or bleeding. - Use cautiously in cardiovascular disease: assess risk of thrombotic events. - Avoid concurrent use with other NSAIDs or anticoagulants unless directed. - Store below 25°C: keep in the original packaging, protect from moisture.

Ibuprofen may interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin) – heightened bleeding risk. - High‑dose aspirin aspirin     - Selective COX‑2 inhibitors (e.g., celecoxib).

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