GNH USA

Europe — EMA

Oxycodone Depot Teva (Oxycodone Hydrochloride)

GNH USA supplies Oxycodone Depot Teva (Oxycodone Hydrochloride), an opioid analgesic for chronic cancer and severe non‑cancer pain.

International sale not permitted. Listed for the domestic market and B2B only.

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What is Oxycodone Hydrochloride?

Oxycodone Hydrochloride, the active ingredient in Oxycodone Depot Teva, is an opioid analgesic presented as a depot formulation for systemic use. It is indicated for the management of moderate to severe chronic pain in adult patients when around‑the‑clock treatment is required. GNH USA supplies Oxycodone Depot Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH USA supplies Oxycodone Depot Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

What is Oxycodone Hydrochloride used for?

Oxycodone Depot Teva is an opioid analgesic used in the management of pain pathways that involve central nociceptive processing. - Chronic cancer pain: provides long‑acting relief for patients with persistent tumor‑related pain. - Post‑surgical pain: maintains analgesia during the postoperative recovery period when oral dosing is not feasible. - Severe non‑cancer chronic pain: offers continuous opioid coverage for conditions such as severe osteoarthritis or neuropathic pain unresponsive to other therapies.

What are the side effects of Oxycodone Hydrochloride?

Oxycodone Depot Teva may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Constipation: reduced gastrointestinal motility leading to hard stools. - Nausea: sensation of queasiness, sometimes progressing to vomiting. - Drowsiness: mild sedation or feeling of fatigue. - Dry mouth: decreased salivary flow causing oral discomfort. - Dizziness: light‑headed sensation, especially when standing quickly. - Pruritus: mild itching without rash.

Serious or Rare Side Effects: - Respiratory depression: slowed breathing that can be life‑threatening. - Severe hypotension: marked drop in blood pressure causing faintness. - Opioid use disorder: dependence or addiction with misuse potential. - Adrenal insufficiency: impaired cortisol production leading to fatigue and weakness. - Severe allergic reaction: anaphylaxis with rash, swelling, and airway compromise. - QT interval prolongation: cardiac rhythm disturbance detectable on ECG.

What precautions apply to Oxycodone Hydrochloride?

When prescribing Oxycodone Depot Teva, clinicians should consider several safety measures to minimize risk. - Assess pain severity and opioid tolerance: ensure the patient requires long‑acting opioid therapy. - Evaluate respiratory function: monitor for signs of depression, especially in opioid‑naïve individuals. - Review concomitant medications: avoid combining with other central nervous system depressants. - Counsel on dependence risk: discuss safe use, storage, and disposal. - Monitor for endocrine effects: watch for signs of adrenal insufficiency or hormonal changes. - Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

What does Oxycodone Hydrochloride interact with?

Oxycodone Depot Teva can interact with a variety of medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Benzodiazepines: combined use markedly increases risk of respiratory depression and profound sedation. - CNS depressants: concurrent administration with alcohol, barbiturates or other sedatives can cause life‑threatening respiratory compromise. - CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise oxy‑dosed plasma levels, heightening toxicity risk.

Moderate Interactions (Monitor Closely): - CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): can reduce conversion to active metabolites, affecting analgesia. - Anticholinergics: may exacerbate constipation and urinary retention. - Diuretics: can increase risk of orthostatic hypotension when combined with opioid‑induced vasodilation.

Frequently asked questions

What is Oxycodone Depot Teva used for?+
Oxycodone Depot Teva is a long‑acting opioid formulation indicated for the management of moderate to severe chronic pain, including cancer‑related pain and severe non‑cancer pain, when continuous around‑the‑clock analgesia is required.
How does oxycodone hydrochloride work in the body?+
Oxycodone hydrochloride binds to μ‑opioid receptors in the central nervous system, activating inhibitory pathways that lower neuronal excitability and reduce the release of pain‑transmitting neurotransmitters, thereby diminishing the perception of pain.
What is the usual dose of Oxycodone Depot Teva?+
The dosage of Oxycodone Depot Teva is individualized by the prescribing clinician based on the patient’s pain severity, opioid tolerance, and clinical response. No fixed regimen is provided here.
Is Oxycodone Depot Teva safe during pregnancy or breastfeeding?+
Opioid use during pregnancy and lactation carries risks, including neonatal respiratory depression and potential for dependence. Use only if the potential benefit justifies the risk, and consult a specialist obstetrician or neonatologist.
How do I order Oxycodone Depot Teva from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Oxycodone Depot compare with other opioid options?+
Compared with immediate‑release oxycodone tablets, the depot formulation provides sustained plasma concentrations, reducing dosing frequency and improving adherence for patients needing continuous analgesia, while sharing a similar safety and side‑effect profile.
What are the storage and handling requirements for Oxycodone Depot Teva?+
Store the product at or below 25 °C in its original packaging, protecting it from moisture, heat and direct sunlight. Keep it out of reach of children and unauthorized personnel.
How is Oxycodone Depot Teva administered?+
The depot formulation is administered by a healthcare professional via the approved route (typically subcutaneous or intramuscular injection) according to the prescribing information, ensuring proper technique and aseptic conditions.
What are the most serious risks associated with Oxycodone Depot Teva?+
The most serious risks include respiratory depression, severe hypotension, opioid use disorder, and rare but life‑threatening allergic reactions such as anaphylaxis. Immediate medical attention is required if these occur.
Who should not use Oxycodone Depot Teva?+
Patients with known hypersensitivity to oxycodone or any formulation components, those with severe respiratory insufficiency, acute or severe asthma, or untreated obstructive sleep apnea should avoid this medication.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Oxycodone Hydrochloride
Route
Oral Use
Manufacturer
Teva B.V
Origin
EU

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