Europe — EMA
Minims Oxybuprocaïnehydrochloride Bausch + Lomb Ireland Limited (Oxybuprocaine Hydrochloride)
GNH USA supplies Minims Oxybuprocaine (Oxybuprocaine Hydrochloride), a local ophthalmic anesthetic for ocular anesthesia. Request a quote for global supply.
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What is Oxybuprocaine Hydrochloride?
Oxybuprocaine Hydrochloride, the active ingredient in Minims Oxybuprocaine, is a local anesthetic presented as a sterile ophthalmic solution for ocular use. It provides temporary loss of corneal sensation for patients undergoing eye examinations or minor procedures.
GNH USA supplies Minims Oxybuprocaine Bausch + Lomb Ireland Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Oxybuprocaine Hydrochloride used for?
Oxybuprocaine Hydrochloride is used as an ophthalmic anesthetic to achieve rapid, reversible loss of corneal sensation.
- Diagnostic eye examinations: provides comfortable, temporary anesthesia for slit‑lamp and fundus evaluation. - Minor ocular surgery: enables painless corneal or conjunctival procedures such as foreign‑body removal. - Contact lens fitting: numbs the ocular surface to improve tolerance during fitting and assessment.
What are the side effects of Oxybuprocaine Hydrochloride?
Adverse reactions are generally mild and transient, but clinicians should be aware of both common and serious possibilities.
Common Side Effects: - Burning or stinging sensation on instillation - Redness of the conjunctiva - Increased tearing - Temporary blurred vision - Mild allergic conjunctivitis - Transient foreign‑body sensation
Serious or Rare Side Effects: - Corneal epithelial toxicity or ulceration - Severe allergic reaction (anaphylaxis) - Persistent corneal edema - Keratitis or infectious keratitis - Elevated intra‑ocular pressure - Vision loss in extreme cases
What precautions apply to Oxybuprocaine Hydrochloride?
Before using Oxybuprocaine Hydrochloride, consider the following safety measures.
- Allergy assessment: avoid use in patients with known hypersensitivity to oxybuprocaine or related ester anesthetics. - Contact lens use: remove lenses before instillation and delay reinsertion until sensation returns. - Pre‑existing ocular disease: use with caution in eyes with corneal epithelial defects or active infection. - Systemic absorption: limit repeated dosing to reduce potential systemic exposure. - Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation. - Store at ambient temperature: keep in original container, protect from light and moisture.
What does Oxybuprocaine Hydrochloride interact with?
Oxybuprocaine Hydrochloride may interact with other ophthalmic agents; awareness of the level of interaction helps guide safe co‑administration.
Major Interactions (Avoid): - Concurrent use of other topical ocular anesthetics: additive corneal toxicity. - Repeated application with topical beta‑blockers: increased risk of corneal epithelial damage.
Moderate Interactions (Monitor Closely): - Systemic sodium channel blockers (e.g., antiarrhythmics): monitor for additive nerve‑conduction effects. - Topical non‑steroidal anti‑inflammatory drugs (NSAIDs): may heighten corneal irritation. - Anticholinergic eye drops: could delay clearance of the anesthetic from the ocular surface.



