Europe — EMA
Oxomemazine Sans Sucre Cristers
GNH USA supplies Oxomemazine Sans Sucre Cristers (Oxomemazine), a first‑generation antihistamine for allergic rhinitis, urticaria and pruritus.
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What is Oxomemazine?
Oxomemazine, the active ingredient in Oxomemazine Sans Sucre Cristers, is a first‑generation antihistamine presented as a tablet for oral use. It is employed to relieve allergic symptoms such as itching, rash and runny nose in children and adults. GNH USA supplies Oxomemazine Sans Sucre Cristers as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Oxomemazine used for?
Oxomemazine is a first‑generation antihistamine that acts on histamine‑H1 receptors to alleviate allergic conditions. - Allergic rhinitis: reduces sneezing, nasal congestion and itching. - Urticaria (hives): diminishes wheal formation and pruritus. - Pruritus of the skin: provides relief from generalized itching associated with allergic reactions.
What are the side effects of Oxomemazine?
Oxomemazine may cause a range of adverse reactions, most of which are dose‑dependent and reversible.
Common Side Effects: - Drowsiness: feeling unusually sleepy or fatigued. - Dry mouth: reduced salivation leading to a sticky sensation. - Dizziness: light‑headed feeling, especially when standing quickly. - Blurred vision: temporary difficulty focusing. - Constipation: slowed gastrointestinal motility.
Serious or Rare Side Effects: - Cardiac arrhythmias: irregular heart rhythm that may require medical attention. - Severe allergic reaction: rash, swelling, or difficulty breathing. - Hepatotoxicity: signs of liver injury such as jaundice. - Extrapyramidal symptoms: involuntary muscle movements or tremor. - Hematologic abnormalities: unexplained bruising or low blood counts.
What precautions apply to Oxomemazine?
When prescribing Oxomemazine, clinicians should consider several safety aspects. - Pregnancy: avoid use unless the benefit outweighs the risk; limited data are available. - Breastfeeding: may pass into milk; weigh benefits against potential infant effects. - Elderly patients: start with lower doses due to increased sensitivity to sedation. - Concomitant CNS depressants: may enhance drowsiness and impair coordination. - Driving or operating machinery: advise patients to assess tolerance before engaging in such activities. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.
What does Oxomemazine interact with?
Oxomemazine can interact with other medicines, altering its efficacy or safety profile.
Major Interactions (Avoid):\n- Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis and excessive sedation. - Other antihistamines: additive sedation and anticholinergic effects. - CNS depressants (e.g., benzodiazepines, opioids): heightened drowsiness and respiratory depression.
Moderate Interactions (Monitor Closely): - Alcohol: may increase sedation and impair judgment. - Anticholinergic drugs: enhanced dry‑mouth and constipation. - CYP450 inhibitors (e.g., erythromycin): possible increase in oxox‑ - CYP



