Europe — EMA
Oxitril (Duloxetine Hydrochloride)
Duloxetine, the active ingredient in Oxitril, is a serotonin‑norepinephrine reuptake inhibitor (SNRI) presented as a tablet for oral use.
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What is Duloxetine Hydrochloride?
Duloxetine, the active ingredient in Oxitril, is a serotonin‑norepinephrine reuptake inhibitor (SNRI) presented as a tablet for oral use. It is indicated for the treatment of major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain in adults. GNH USA supplies Oxitril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Oxitril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Duloxetine Hydrochloride used for?
Duloxetine acts on central nervous system pathways that regulate mood and pain perception.
- Major depressive disorder: alleviates depressive symptoms and improves functional outcomes. - Generalized anxiety disorder: reduces anxiety severity and associated physical symptoms. - Diabetic peripheral neuropathic pain: lessens pain intensity and improves quality of life. - Fibromyalgia: decreases widespread musculoskeletal pain and fatigue. - Chronic musculoskeletal pain: provides relief from chronic low back and osteoarthritis pain.
What are the side effects of Duloxetine Hydrochloride?
Duloxetine may cause a range of adverse reactions, from mild to serious.
Common Side Effects: - Nausea - Dry mouth - Somnolence - Constipation - Increased sweating - Dizziness
Serious or Rare Side Effects: - Hepatotoxicity - Hypertensive crisis - Serotonin syndrome - Severe skin reactions (Stevens‑Johnson syndrome) - Suicidal thoughts or behaviors - Angle‑grating
What precautions apply to Duloxetine Hydrochloride?
When using Dul…
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