Europe — EMA
Oxis Turbuhaler (Formoterol Fumarate Dihydrate)
Formoterol fumarate dihydrate, the active ingredient in Oxis Turbuhaler, is a long‑acting β‑adrenergic agonist (LABA) presented as a dry‑powder inhalation formulation for oral inhalation use.
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What is Formoterol Fumarate Dihydrate?
Formoterol fumarate dihydrate, the active ingredient in Oxis Turbuhaler, is a long‑acting β‑adrenergic agonist (LABA) presented as a dry‑powder inhalation formulation for oral inhalation use. It provides bronchodilation for maintenance therapy in asthma and chronic obstructive pulmonary disease (COPD) in adults.
GNH USA supplies Oxis Turbuhaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Formoterol Fumarate Dihydrate used for?
Formoterol fumarate dihydrate is a bronchodilator that acts on the airway smooth‑muscle pathway to improve airflow. - Asthma: improves lung function and reduces symptoms when used regularly as maintenance therapy. - Chronic obstructive pulmonary disease (COPD): provides sustained bronchodilation to ease breathing and decrease exacerbation risk. - Exercise‑induced bronchoconstriction: helps prevent airway narrowing during physical activity when combined with a rapid‑onset reliever.
What are the side effects of Formoterol Fumarate Dihydrate?
Formoterol may cause adverse reactions that vary in frequency and severity.
Common Side Effects: - Tremor: mild shaking of the hands or limbs. - Headache: transient headache episodes. - Throat irritation: discomfort or dryness in the throat. - Cough: occasional coughing after inhalation. - Palpitations: sensation of rapid or irregular heartbeat.
Serious or Rare Side Effects: - Paradoxical bronchospasm: sudden worsening of breathing difficulty. - Cardiovascular events: chest pain, arrhythmia, or hypertension. - Hypokalemia: low blood potassium levels. - Severe allergic reaction: rash, swelling, or anaphylaxis.
What precautions apply to Formoterol Fumarate Dihydrate?
When prescribing Formoterol, clinicians should consider several safety aspects. - Assess asthma or COPD control: ensure patient is stable before initiating therapy. - Review cardiovascular history: patients with arrhythmias or ischemic heart disease need careful monitoring. - Avoid excessive dosing: do not exceed the recommended daily inhalations. - Monitor for paradoxical bronchospasm: discontinue if breathing worsens after use. - Store at ambient temperature: keep below 25°C, retain in original packaging, and protect from moisture.
What does Formoterol Fumarate Dihydrate interact with?
Formoterol can interact with other medications that affect the cardiovascular or respiratory systems.
Major Interactions (Avoid):\n- Non‑selective β‑blockers: antagonize bronchodilator effect and may precipitate bronchospasm. - Mono‑mono t - t - \
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