Oxatrex (Ofloxacin)

Ofloxacin, the active ingredient in Oxatrex, is a fluoroquinolone antibiotic presented as a strength/form for oral use. It treats a variety of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH USA supplies Oxatrex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Oxatrex is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria in several organ systems. - Urinary tract infection: helps eradicate *U coli* and other common uropathogens. - Respiratory tract infection: aids in clearing *Streptococcus pneumoniae* and *Haemophilus influenzae*. - Skin and soft‑tissue infection: assists in eliminating *Staphylococcus aureus* including methicillin‑sensitive strains. - Gonorrhoea: provides bacterial clearance in uncomplicated cases. - Prostatitis chronic: contributes to bacterial eradication in chronic prostatitis caused by susceptible organisms.

Adverse reactions to Ofloxacin may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Nausea: mild gastrointestinal upset. - Diarrhea: loose stools, often self‑limiting. - Headache: transient cranial discomfort. - Dizziness: occasional vertigo or light‑headedness. - Rash: mild skin erythema or itching. - Photosensitivity: increased skin sensitivity to sunlight.

Serious or Rare Side Effects: - Tendon rupture: sudden pain or loss of function, especially in the Achilles. - QT prolongation: cardiac rhythm disturbances that may cause palpitations. - Severe allergic reaction: anaphylaxis, swelling of face or throat. - Peripheral neuropathy: numbness or tingling in extremities. - Clostridioides difficile colitis: severe diarrhea with abdominal pain. - Hepatotoxicity: elevated liver enzymes or jaundice.

Before initiating Ofloxacin therapy, clinicians should assess patient history and risk factors. - Renal impairment: adjust dose or avoid if severe. - Hepatic dysfunction: monitor liver function tests. - History of tendon disorders: avoid in patients with prior tendon injury. - Cardiac arrhythmia risk: caution in patients with prolonged QT interval. - Pregnancy and lactation: use only if clearly needed; discuss risks with obstetrician. - Store at below 25°C: keep in original packaging, protect from moisture and direct sunlight.

Ofloxacin may interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Antacids containing aluminium or magnesium: reduce Ofloxacin absorption. - Warfarin: may increase anticoagulant effect, raising bleeding risk. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): heightened risk of CNS stimulation.

Moderate Interactions (Monitor Closely): - Corticosteroids: increased chance of tendon injury. - Theophylline: possible increase in plasma concentration. - Cyclosporine: may raise Ofloxacin levels, requiring monitoring.