Europe — EMA
Otrivin (Xylometazoline Hydrochloride)
Xylometazoline hydrochloride, the active ingredient in Otrivin, is an alpha‑2‑adrenergic agonist presented as a nasal spray for topical intranasal use.
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What is Xylometazoline Hydrochloride?
Xylometazoline hydrochloride, the active ingredient in Otrivin, is an alpha‑2‑adrenergic agonist presented as a nasal spray for topical intranasal use. It relieves nasal congestion associated with colds, sinusitis and allergic rhinitis in adults and children. GNH USA supplies Otrivin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
GNH USA supplies Otrivin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Xylometazoline Hydrochloride used for?
Otrivin acts on the nasal mucosa to reduce swelling and improve airflow.
- Common cold: alleviates nasal congestion and improves breathing. - Sinusitis: reduces mucosal edema, facilitating sinus drainage. - Allergic rhinitis: decreases nasal blockage caused by allergic inflammation. - Nasal surgery recovery: helps maintain clear nasal passages post‑operatively.
What are the side effects of Xylometazoline Hydrochloride?
Adverse reactions are generally mild and related to local irritation of the nasal mucosa.
Common Side Effects: - Burning sensation: mild burning or stinging feeling in the nose. - Nasal dryness: sensation of dryness or crusting inside the nostrils. - Sneezing: transient sneezing episodes after application. - Headache: mild headache associated with nasal decongestion.
Serious or Rare Side Effects: - Rebound congestion: worsening nasal blockage after prolonged use. - Nasal ulceration: rare ulcer formation on the nasal mucosa. - Severe allergic reaction: hives, swelling, or difficulty breathing. - Hypertensive crisis: rare elevation of blood pressure in susceptible individuals.
What precautions apply to Xylometazoline Hydrochloride?
Before using Otrivin, consider the following safety measures:
- Contraindication: Do not use if - Pregnancy - ewline - ewline - ewline - - - ewline --- --- - ",
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