GNH USA

Europe — EMA

Otrivin (Xylometazoline Hydrochloride)

Xylometazoline hydrochloride, the active ingredient in Otrivin, is an Alpha‑2‑adrenergic agonist presented as a nasal spray for topical intranasal use.

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What is Xylometazoline Hydrochloride?

Xylometazoline hydrochloride, the active ingredient in Otrivin, is an Alpha‑2‑adrenergic agonist presented as a nasal spray for topical intranasal use. It relieves nasal congestion caused by colds, sinusitis and allergic rhinitis in adults and children. GNH USA supplies Otrivin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Otrivin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Xylometazoline Hydrochloride used for?

Otrivin is an alpha‑2‑adrenergic agonist that reduces nasal airway resistance in several upper‑respiratory conditions.

- Common cold: temporary relief of nasal congestion. - Acute sinusitis: decreases swelling of the nasal mucosa. - Allergic rhinitis: eases blockage caused by allergic inflammation. - Nasal surgery recovery: helps maintain airway patency post‑operatively.

What are the side effects of Xylometazoline Hydrochloride?

Adverse reactions are generally mild and related to local irritation of the nasal mucosa.

Common Side Effects: - Burning sensation: mild burning or stinging at the application site. - Nasal dryness: dryness or crusting inside the nose. - Sneezing: transient sneezing after spray use. - Headache: mild headache in some users. - Epistaxis: occasional nosebleeds. - Taste disturbance: altered taste perception.

Serious or Rare Side Effects: - Severe nasal irritation: intense burning or ulceration. - Rebound congestion: worsening nasal blockage after prolonged use. - Allergic reaction: rash, itching, swelling or difficulty breathing. - Hypertension: elevated blood pressure in susceptible individuals. - Cardiac arrhythmia: irregular heartbeat in rare cases. - Anaphylaxis: life‑threatening systemic allergic response.

What precautions apply to Xylometazoline Hydrochloride?

Before using Otrivin, consider the following safety measures:

- Age restriction: not recommended for children under 6 years without medical advice. - Duration limit: limit usage to 3‑7 days to avoid rebound congestion. - Pre‑existing conditions: use cautiously in patients with hypertension, heart disease, diabetes mellitus. - Pregnancy and lactation: consult the professional for risk assessment before use. - Drug interactions: review concomitant nasal medications before use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Xylometazoline Hydrochloride interact with?

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Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Haleon Czech Republic S.R.O.
Origin
EU

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