Otrinazil (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline hydrochloride, the active ingredient in Otrinazil, is an alpha‑adrenergic agonist presented as a nasal spray for topical intranasal use. It relieves nasal congestion associated with common colds, sinusitis, and allergic rhinitis in adults and children. GNH USA supplies Otrinazil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH USA supplies Otrinazil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Otrinazil, a topical nasal decongestant, acts on the nasal mucosa to reduce swelling and improve airflow.

- Common cold: alleviates nasal congestion and improves breathing. - Sinusitis: reduces mucosal edema, facilitating sinus drainage. - Allergic rhinitis: decreases nasal passage swelling caused by allergens. - Nasal surgery recovery: helps maintain airway patency post‑operatively.

Adverse reactions to Otrinazile may arise from local irritation or systemic absorption.

Common Side Effects: - Burning sensation: mild burning or stinging in the nostrils. - Nasal dryness: dryness or crusting of the nasal mucosa. - Sneezing: transient sneezing episodes after application. - Headache: mild headache associated with decongestion. - Epistaxis: occasional nosebleeds due to mucosal irritation.

Serious or Rare Side Effects: - Rebound congestion: worsening nasal blockage after prolonged use. - Hypertensive crisis: significant rise in blood pressure in susceptible individuals. - Cardiac arrhythmia: irregular heart rhythm in patients with pre‑existing heart disease. - Severe allergic reaction: rash, itching, swelling, or anaphylaxis. - Local infection: secondary bacterial infection of the nasal mucosa.

When using Otrinazil, consider the following safety measures:

- Duration: limit the treatment to no more than 3 days to avoid rebound congestion. - Pre‑existing conditions : avoid use if you have any cardiovascular disease or hypertension or severe risk the    g   g \

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