Europe — EMA
Ostac (Clodronate Disodium)
Clodronate disodium, the active ingredient in Ostac, is a bis‑bisphosphonate presented as a tablet for oral use. It is used to treat bone‑related conditions such as osteoporosis and to manage bone pain in certain…
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What is Clodronate Disodium?
Clodronate disodium, the active ingredient in Ostac, is a bis‑bisphosphonate presented as a tablet for oral use. It is used to treat bone‑related conditions such as osteoporosis and to manage bone pain in certain cancers.
GNH USA supplies Ostac as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.
What is Clodronate Disodium used for?
Ostac acts on the skeletal system to modify bone turnover in several clinical contexts.
- Osteoporosis: helps reduce the risk of vertebral fractures in post‑menopausal women and men at high risk. - Bone metastases: alleviates pain and slows progression of skeletal‑related events. - Hyper‑hormone related hyper‑calcemia: reduces serum calcium levels associated with malignancy. - Paget’s disease of bone : improves bone remodelling and decreases osteoclastic activity in affected areas. - Primary osteolytic lesions in multiple myeloma : decreases bone resorption and pain at lesion sites . -



