Europe — EMA
Ospolot (Sultiame)
GNH USA supplies Ospolot (Sultiame), a carbonic anhydrase inhibitor indicated for the management of edema and hypertension. Request a quote for global supply.
Request sourcing
What is Sultiame?
Sultiame, the active ingredient in Ospolot, is a carbonic anhydrase inhibitor presented as an oral tablet for oral use. It treats edema and hypertension in patients who require diuretic therapy.
GNH USA supplies Ospolot as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Sultiame used for?
Sultiame acts on renal carbonic anhydrase to promote fluid loss, making Ospolot useful in conditions that benefit from diuresis.
- Edema: reduces excess fluid accumulation and swelling. - Hypertension: lowers elevated blood pressure by increasing urinary sodium and water excretion.
What are the side effects of Sultiame?
Common side effects are generally mild and related to its diuretic action.
Common Side Effects: - Headache: mild to moderate intensity. - Dizziness: especially on standing. - Nausea: occasional gastrointestinal upset. - Fatigue: feeling of reduced energy. - Increased urination: expected diuretic response. - Mild electrolyte imbalance: low potassium or sodium.
Serious or Rare Side Effects: - Severe metabolic acidosis: significant blood pH drop. - Kidney stones: due to altered urine composition. - Allergic reactions: rash, itching, or swelling. - Blood disorders: rare agranulocytosis or leukopenia. - Severe dehydration: excessive fluid loss. - Hepatic dysfunction: abnormal liver enzymes.
What precautions apply to Sultiame?
Patients should be evaluated for factors that could increase risk while using Ospolot.
- Renal function: monitor in patients with impaired kidneys. - Electrolytes: check serum potassium and sodium regularly. - Gout: may precipitate gout attacks. - Pregnancy: use only if benefit outweighs potential risk. - Drug interactions: review all concomitant medicines. - Store at ambient temperature: keep in the original pack, protect from moisture.
What does Sultiame interact with?
Ospolot can affect or be affected by several other medicines.
Major Interactions (Avoid): - Loop diuretics: may cause excessive diuresis. - Lithium: can increase lithium serum levels. - Corticosteroids: may enhance electrolyte loss.
Moderate Interactions (Monitor Closely): - ACE inhibitors: additive blood pressure lowering. - NSAIDs: may reduce diuretic efficacy.
