Osaver Hct (Olmesartan Medoxomil, Hydrochlorothiazide)

Olmesartan medoxil and hydrochlorothiazide, the active ingredients in Osaver Hct, are an angiotensin II receptor blocker combined with a thiazide diuretic presented as a tablet for oral use. It is used to lower blood pressure in adults with hypertension.

GNH USA supplies Osaver Hct as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑controlled batches and regulatory compliance across EU and other markets.

Osaver Hct, a combination antihypertensive, acts on the renin‑angiotensin system and promotes diuresis to manage high blood pressure.

- Hypertension: reduces systolic and diastolic blood pressure in adults with essential hypertension. - High‑risk cardiovascular patients: helps achieve target blood pressure when monotherapy is insufficient. - Patients requiring diuretic therapy: adds fluid‑excreting effect to improve blood pressure control.

Common Side Effects: - Dizziness: feeling light‑headed, especially after standing. - Headache: mild to moderate pain in the head region. - Fatigue: general tiredness or lack of energy. - Increased urination: more frequent need to void. - Electrolyte imbalance: low potassium or sodium levels. - Dry mouth: reduced salivation.

Serious or Rare Side Effects: - Severe hypotension: dangerously low blood pressure. - Kidney impairment: reduced renal function or acute kidney injury. - Hyperkalemia: elevated potassium levels. - Angioedema: swelling of face, lips, tongue, or throat. - Pancreatitis: inflammation of the pancreas. - Anaphylactic reaction: severe allergic response requiring emergency care.

Before starting Osaver Hct, consider the following precautions: - Monitor blood pressure: ensure adequate control and avoid excessive lowering. - Assess renal function: check creatinine and eGFR regularly. - Check electrolytes: especially potassium and sodium levels. - Avoid use in pregnancy: drug may harm the fetus. - Use caution in liver disease: dose adjustment may be needed. - Store at room temperature: keep in the original container, protect from moisture and light.

Osaver Hct can interact with several medicines. Review the following groups:

Major Interactions (Avoid): - Aliskiren (in diabetic patients): combined use may increase risk of renal dysfunction. - Potassium‑sparing diuretics (e.g., spironolactone): may cause hyperkalemia. - NSAIDs (e.g., ibuprofen): can blunt antihypertensive effect and affect kidney function. - Lithium: increased lithium levels and toxicity risk.

Moderate Interactions (Monitor Closely): - ACE inhibitors: additive blood pressure lowering, monitor for hypotension. - Beta‑blockers: may enhance antihypertensive effect, watch for bradycardia. - Antidiabetic agents: diuretic may affect glucose control, adjust monitoring as needed.