GNH USA

Europe — EMA

Orpidix (Ketotifen)

GNH USA supplies Orpidix (Ketotifen), an antihistamine for allergic rhinitis, urticaria and conjunctivitis. Request a quote for global supply.

Ketotifen

Request sourcing

1
Pack/s

What is Ketotifen?

Ketotifen, the active ingredient in Orpidix, is an antihistamine presented as a tablet for oral use. It is used to manage allergic conditions such as seasonal allergic rhinitis and chronic urticaria in adults and children.

GNH USA supplies Orpidix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

What is Ketotifen used for?

Orpidix (ketotifen) acts on allergic pathways to reduce histamine‑mediated symptoms. - Seasonal allergic rhinitis: helps relieve nasal congestion, itching and sneezing. - Chronic idiopathic urticaria: reduces the frequency and severity of hives. - Allergic conjunctivitis: alleviates eye itching and redness.

What are the side effects of Ketotifen?

Ketotifen is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Drowsiness: mild to moderate sleepiness. - Dry mouth: reduced salivation. - Headache: occasional tension‑type headache. - Weight gain: modest increase over prolonged use. - Gastrointestinal discomfort: nausea or mild abdominal pain.

Serious or Rare Side Effects: - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Hematologic abnormalities: eosinophilia or neutropenia. - Cardiac arrhythmias: rare QT‑interval changes. - Anaphylaxis: acute, life‑threatening hypersensitivity.

What precautions apply to Ketotifen?

Before using Orpidix, consider the following safety measures: - Pregnancy: limited data; use only if clearly needed. - Breastfeeding: excreted in milk; weigh benefits against risks. - Elderly: start with lower dose and monitor for sedation. - Liver impairment: dose adjustment may be required. - Concomitant CNS depressants: may increase drowsiness. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Ketotifen interact with?

Ketotifen may interact with several drug classes. Review the following interactions:

Major Interactions (Avoid):\n- MAO inhibitors: risk of hypertensive crisis. - QT‑prolonging agents: additive risk of cardiac arrhythmia.

Moderate Interactions (Monitor Closely): - Alcohol: enhances sedative effect. - Other antihistamines: may increase anticholinergic burden. - CYP3A4 inhibitors: may raise ketotifen plasma levels. - CNS depressants: heightened drowsiness. - Antacids containing aluminum or magnesium: may reduce absorption.

Frequently asked questions

What conditions is Orpidix used to treat?+
Orpidix contains ketotifen, an antihistamine that is prescribed to relieve symptoms of seasonal allergic rhinitis, chronic idiopathic urticaria and allergic conjunctivitis. It works by reducing histamine release and blocking H1 receptors, helping to control nasal congestion, itching, sneezing and eye irritation associated with these allergic disorders.
How does ketotifen work in the body?+
Ketotifen stabilises mast cells, preventing them from releasing histamine and other inflammatory mediators during an allergic response. It also antagonises histamine at H1 receptors, which diminishes the downstream effects of histamine such as vasodilation, itching and mucus production, providing overall symptom relief.
What is the usual dose of Orpidix?+
The appropriate dose of Orpidix is determined by the prescribing clinician based on the patient’s age, severity of symptoms and overall health status. Healthcare professionals tailor the regimen to achieve optimal control of allergic symptoms while minimising potential side effects.
Is Orpidix safe to use during pregnancy or while breastfeeding?+
Safety data for ketotifen in pregnancy are limited, so the drug should only be used when the potential benefit justifies any possible risk to the fetus. Ketotifen is excreted in breast‑milk; therefore, nursing mothers should discuss the risk‑benefit balance with their healthcare provider before use.
How do I order Orpidix from GNH USA?+
To request Orpidix, submit an enquiry on the product page at gnh-usa.com indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Orpidix compare with other antihistamines?+
Compared with first‑generation antihistamines, ketotifen offers both H1‑receptor blockade and mast‑cell stabilisation, which can provide longer‑lasting symptom control and a lower incidence of anticholinergic side effects such as dry mouth and blurred vision. It is generally considered more suitable for chronic allergic conditions than short‑acting agents.
What are the recommended storage conditions for Orpidix?+
Orpidix tablets should be stored at ambient temperature, ideally below 25 °C, in their original packaging to protect them from moisture and direct sunlight. Keeping the product in a dry, cool place helps maintain its potency throughout its shelf life.
How is Orpidix administered?+
Orpidix is supplied as oral tablets that are taken with water. The prescribing clinician will advise whether the medication should be taken with or without food, and the frequency of dosing, based on the individual’s therapeutic needs.
What are the most serious risks associated with Orpidix?+
Serious adverse reactions to ketotifen, though rare, can include severe skin reactions such as Stevens‑Johnson syndrome, liver injury, blood‑cell abnormalities and cardiac arrhythmias. Patients should seek immediate medical attention if they notice rash, jaundice, unexplained bruising or irregular heartbeat.
Who should not take Orpidix?+
Orpidix is contraindicated in individuals with known hypersensitivity to ketotifen or any other component of the formulation. Caution is also advised for patients with severe liver disease, uncontrolled cardiac conditions, or those taking medications that may cause dangerous drug interactions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Ketotifen
Route
Oral Use
Manufacturer
Proel Epam G Koronis Sa Pharmaceuticals
Origin
EU

Related products

Brunistill

Brunistill

Ketotifen

Bruschettini S.R.L
EU
Chetotifene Mylan Generics

Chetotifene Mylan Generics

Ketotifen

Mylan S.P.A.
EU
Ketof

Ketof

Ketotifen

Hexal Ag
EU
Ketotifen

Ketotifen

Ketotifen

Help Abee
EU