Orocalm (Benzydamine Hydrochloride)

Benzydamine Hydrochloride, the active ingredient in Orocalm, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oromucosal preparation for local use. It provides anti‑inflammatory, analgesic and antiseptic effects for sore throat, oral mucositis, mouth ulcers and other inflammation of the oral cavity in appropriate patients.

GNH USA supplies Orocalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Benzydamine Hydrochloride acts locally on inflamed oral tissues, relieving pain and reducing inflammation. - Sore throat: provides symptomatic relief of pain and swelling in the pharyngeal mucosa. - Oral mucositis: reduces inflammation and discomfort associated with chemotherapy or radiotherapy‑induced mucosal injury. - Mouth ulcers: promotes analgesia and supports healing of aphthous lesions. - Inflammation of the oral cavity: alleviates general irritation and redness of the oral mucosa.

Benzydamine Hydrochloride is generally well tolerated when applied to the oral mucosa, but some adverse reactions may occur.

Common Side Effects: - Mild burning or stinging sensation at the application site. - Transient alteration of taste. - Slight oral irritation or redness. - Dry mouth sensation. - Minor swelling of the lips.

Serious or Rare Side Effects: - Allergic reactions such as urticaria, angioedema or anaphylaxis. - Severe oral mucosal ulceration or necrosis. - Contact dermatitis of the perioral skin.

Before using Orocalm, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: use with caution and under medical advice. - Age: follow prescriber guidance for pediatric or elderly patients. - Known hypersensitivity: avoid if allergic to benzydamine or related compounds. - Concurrent oral infections: monitor for worsening symptoms. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Benzydamine Hydrochloride may interact with other agents applied to the oral cavity.

Major Interactions (Avoid): - Concurrent use with other topical NSAIDs: may increase local irritation. - Alcohol consumption immediately after application: can enhance mucosal burning.

Moderate Interactions (Monitor Closely): - Systemic anticoagulants: monitor for increased bleeding if mucosal lesions develop. - Chemotherapeutic agents: watch for additive mucosal toxicity. - Other oral antiseptics or mouthwashes: risk of cumulative irritation.