Europe — EMA
Optalgin (Metamizole Sodium)
Metamizole sodium, the active ingredient in Optalgin, is a non‑stensive analgesic presented as a 500 mg tablet for oral use. It is employed to relieve moderate to severe pain and to reduce fever in adult patients.
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What is Metamizole Sodium?
Metamizole sodium, the active ingredient in Optalgin, is a non‑stensive analgesic presented as a 500 mg tablet for oral use. It is employed to relieve moderate to severe pain and to reduce fever in adult patients.
GNH USA supplies Optalgin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Metamizole Sodium used for?
Metamizole sodium is used in the management of pain and fever across several clinical contexts. - Post‑operative pain: provides effective analgesia after surgical procedures. - Cancer‑related pain: helps control moderate to severe pain in oncology patients. - High‑grade fever: reduces elevated body temperature when other antipyretics are insufficient.
What are the side effects of Metamizole Sodium?
Adverse reactions to Metamizole sodium vary in frequency and severity.
Common Side Effects: - Nausea: mild gastrointestinal upset. - Dizziness: transient light‑headedness. - Rash: mild skin irritation. - Elevated liver enzymes: mild, reversible changes in liver function tests.
Serious or Rare Side Effects: - Agranulocytosis: potentially life‑threatening drop in white‑blood cells. - Severe allergic reactions: including anaphylaxis and angio‑edema. - Hepatotoxicity: significant liver injury. - Blood dyscrasias: such as thrombocytopenia or hemolytic anemia.
What precautions apply to Metamizole Sodium?
When using Metamizole sodium, several safety considerations are recommended. - Renal function monitoring: assess kidney health before and during therapy. - Hepatic function monitoring: check liver enzymes periodically. - Blood count monitoring: perform regular complete blood counts to detect agranulocytosis early. - Contra‑indication in known allergy: avoid use if hypersensitivity to metamizole or related compounds exists. - Use in pregnancy: assess risk‑benefit — the drug is generally not recommended for routine use in pregnancy. - Store at below 25°C: keep in the original pack ; protect from moisture.
What does Metamizole Sodium interact with?
Metamizole sodium may interact with several medications, requiring attention to avoid reduced efficacy or increased toxicity.
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