Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine, the active ingredient in Ophtesic, is a local anesthetic presented as a sterile ophthalmic solution for topical ocular use. It provides rapid, reversible numbing of the corneal surface and conjunctiva, facilitating procedures such as tonometry, foreign body removal, and minor eye surgeries in adult patients. It is commonly used by ophthalmologists and optometrists for patient comfort during examinations.

GNH USA supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks and regulatory compliance across EU and other markets.

Ophtesic delivers lidocaine as a topical local anesthetic for ophthalmic procedures.

- Corneal abrasion: provides analgesia to enable comfortable healing and examination. - Foreign body removal: numbs the ocular surface to reduce pain during extraction. - Tonometry: diminishes discomfort during intra‑ocular pressure measurement. - Minor ocular surgery: supplies local anesthesia for procedures such as conjunctival biopsy.

Topical ocular administration of lidocaine may be associated with a range of adverse reactions.

Common Side Effects: - Burning or stinging sensation at the application site. - Transient redness of the conjunctiva. - Temporary blurred vision. - Mild allergic itching or rash.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) requiring emergency care. - Corneal epithelial defect or ulceration with prolonged use. - Persistent epithelial defect leading to delayed healing. - Systemic toxicity (e.g., CNS symptoms such as dizziness, seizures) if excessive absorption occurs.

Prior to using Ophtesic, consider the following precautions: - Allergy assessment: avoid in patients with known hypersensitivity to lidocaine or related amide anesthetics. - Pregnancy: use only if the potential benefit justifies the potential risk to the fetus. - Breastfeeding: caution advised due to minimal systemic absorption; evaluate risk versus benefit. - Contact lens wearers: remove lenses before application to prevent irritation. - Dosage: apply only the prescribed amount and frequency to limit systemic exposure. - Store at ambient temperature: keep in the original container, protect from light and moisture.

Ophtesic may interact with other medicines; awareness of these interactions helps ensure safety.

Major Interactions (Avoid): - Concurrent use of other local anesthetics: additive risk of systemic toxicity. - Class I antiarrhythmic agents (e.g., quinidine, procainamide): may potentiate lidocaine‑related cardiotoxicity.

Moderate Interactions (Monitor Closely): - CYP3A4 inhibitors (e.g., erythromycin, cimetidine): can increase lidocaine plasma concentrations. - Beta‑blockers (e.g., propranolol): may enhance central nervous system effects of lidocaine.