Ophtesic (Anhydrous Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Ophtesic, is a local anesthetic presented as a topical solution for ocular use. It provides topical ocular anesthesia for diagnostic or therapeutic procedures and relief of ocular surface pain.

GNH USA supplies Ophtesic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Ophtesic (lidocaine hydrochloride) is used as a topical ocular anesthetic for procedures involving the eye surface.

- Diagnostic ocular procedures: provides anesthesia to facilitate examination and testing. - Therapeutic ocular procedures: enables painless administration of treatments such as laser therapy. - Ocular surface pain: relieves discomfort from corneal abrasions, foreign bodies or postoperative irritation.

Common Side Effects: - Transient burning sensation at the application site. - Mild stinging or itching. - Temporary blurred vision. - Tear film disturbance or increased tearing. - Mild conjunctival hyperemia. - Slight eyelid edema.

Serious or Rare Side Effects: - Corneal epithelial toxicity or ulceration. - Allergic contact dermatitis of the eyelid or conjunctiva. - Severe ocular inflammation or uveitis. - Vision loss (rare). - Persistent epithelial defect. - Systemic signs of lidocaine toxicity (very rare).

Before using Ophtesic, consider the following precautions: - Allergy assessment: verify no known hypersensitivity to lidocaine or amide anesthetics. - Eye condition: avoid use in infected, inflamed, or compromised ocular surfaces unless directed by a clinician. - Contact lens: remove contact lenses prior to administration. - Systemic absorption: limit use in patients with severe cardiac conduction disorders. - Pregnancy and lactation: use only if the expected benefit outweighs potential risk; consult the prescriber. - Store at room temperature: keep in the original container, protect from light and moisture.

Lidocaine hydrochloride may interact with other agents when used ocularly.

Major Interactions (Avoid): - Systemic local anesthetics: concurrent use may increase plasma lidocaine levels. - Class I antiarrhythmic drugs (e.g., quinidine): additive cardiac effects.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may potentiate bradycardia if systemic absorption occurs. - CYP3A4 inhibitors: may affect metabolism of systemically absorbed lidocaine. - Other ophthalmic solutions: may alter drug absorption or cause formulation incompatibility.