Opexa (Bilastine)

Bilastine, the active ingredient in Opexa, is an antihistamine presented as a tablet for oral use. It treats allergic rhinitis and chronic urticaria in adults and children over 12 years of age.

GNH USA supplies Opexa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Bilastine is an antihistamine that works on the histamine H1‑receptor pathway to relieve allergy‑related symptoms. - Allergic rhinitis: reduces sneezing, nasal itching and runny nose. - Chronic spontaneous urticaria: decreases the number and size of hives and associated itching. - Seasonal allergy symptoms: provides relief from pollen‑induced nasal and ocular discomfort.

Bilastine is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Headache: mild to moderate intensity. - Dry mouth: transient sensation of oral dryness. - Drowsiness: occasional mild sedation. - Fatigue: feeling of reduced energy. - Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects: - Anaphylaxis: acute, potentially life‑threatening allergic reaction. - Stevens‑Johnson syndrome: severe skin and mucous membrane disorder. - Hepatotoxicity: abnormal liver enzyme elevations. - Cardiac arrhythmia: irregular heart rhythm reported in rare cases.

When using Bilastine, consider the following safety measures: - Pregnancy: limited data; use only if clearly needed. - Breastfeeding: excreted in milk; weigh benefits against risks. - Renal impairment: dose adjustment may be required. - Concomitant alcohol or CNS depressants: may increase drowsiness. - Age: safety not established in children under 12 years. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Bilaxine may interact with several medicines; monitoring is advised.

Major Interactions (Avoid): - Ketoprofen: may increase bilastine plasma levels. - Erythromycin: can raise bilatomic ...