Europe — EMA
Ondansetron Teva (Ondansetron Hydrochloride Dihydrate)
Ondansetron Hydrochloride Dihydrate, the active ingredient in Ondansetron Teva, is a 5-HT3 receptor antagonist presented as a tablet for oral use.
Request sourcing
What is Ondansetron Hydrochloride Dihydrate?
Ondansetron Hydrochloride Dihydrate, the active ingredient in Ondansetron Teva, is a 5-HT3 receptor antagonist presented as a tablet for oral use. It treats and helps prevent nausea and vomiting associated with chemotherapy, radiation therapy, and postoperative recovery in adults and children. GNH USA supplies Ondansetron Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
GNH USA supplies Ondansetron Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.
What is Ondansetron Hydrochloride Dihydrate used for?
Ondansetron Teva is a selective 5‑HT3 receptor antagonist used in the management of nausea and vomiting pathways.
- Chemotherapy‑induced nausea and vomiting: reduces the frequency and severity of acute and delayed episodes. - Radiation‑induced nausea and vomiting: helps control nausea during and after radiotherapy. - Post‑operative nausea and vomiting: prevents vomiting in the immediate postoperative period. - Pregnancy‑associated nausea (when prescribed): may be used under specialist supervision to alleviate severe nausea. - Hyper‑emesis gravidarum: provides symptom relief in severe cases when other treatments are insufficient.
What are the side effects of Ondansetron Hydrochloride Dihydrate?
Side effects of ondansetron are generally mild and dose‑dependent.
Common Side Effects: - Headache: mild to moderate intensity. - Constipation: occasional bowel movement difficulty. - Diarrhoea: loose stools in a minority of patients. - Fatigue: feeling of tiredness or reduced energy. - Dizziness: transient light‑headed sensations.
Serious or Rare Side Effects: - Cardiac arrhythmia: QT‑interval prolongation, especially with IV use. - Severe allergic reaction: rash, itching, swelling, or anaphylaxis. - Serotonin syndrome: rare when combined with other serotonergic agents. - Hepatic dysfunction: elevated liver enzymes in susceptible individuals. - Vision changes: blurred vision or visual disturbances.
What precautions apply to Ondansetron Hydrochloride Dihydrate?
When using Ondansetron Teva, consider the following precautions to ensure safe and effective therapy.
- Cardiac monitoring: assess baseline ECG in patients with known heart rhythm disorders. - Electrolyte balance: correct hypokalemia or hypomagnesemia before initiation. - Concomitant serotonergic drugs: evaluate risk of serotonin syndrome. - Pregnancy and lactation: weigh benefits against potential risks; use only if clearly needed. - Renal or hepatic impairment: dose adjustment may be required based on clinical judgement. - Store at below 25°C: keep in the original packaging, protect from moisture and direct light.
What does Ondansetron Hydrochloride Dihydrate interact with?
Ondansetron may interact with several medications, altering its efficacy or safety profile.
Major Interactions (Avoid): - Apatinol (Apixapine?) - Monodun g ) g g -
Moderate g t g t g t g
g t g - g - t - g - - g - t - g - t g - - g - - t - g - - g - - t g - t - - g - - g - - g de t - g - - g de - - g de - t - - g de - t - ",



