Omeprazol Azevedos (Omeprazole Sodium)

Omeprazole, the active ingredient in Omeprazol Azevedos, is a proton pump inhibitor presented as a tablet for oral use. It reduces stomach acid production and is used to treat conditions such as gastro‑reflux disease and related disorders in adults.

GNH USA supplies Omeprazol Azevedos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

Omeprazol Azevedos is a proton pump inhibitor that acts on the gastric acid secretion pathway. - Gastro‑esophageal reflux disease (GERD): provides relief of heartburn and promotes healing of erosive esophagitis. - Peptic ulcer disease: supports ulcer healing by maintaining a less acidic gastric environment. - Zollinger‑Ellison syndrome: controls excessive gastric acid secretion associated with the condition.

Adverse reactions to Omeprazol Azevedos may vary in frequency and severity.

Common Side Effects: - Headache: mild to moderate intensity. - Diarrhea: loose stools occurring intermittently. - Nausea: feeling of stomach discomfort or queasiness. - Abdominal pain: cramping or discomfort in the stomach area. - Flatulence: increased intestinal gas. - Constipation: reduced bowel movements.

Serious or Rare Side Effects: - Clostridioides difficile infection: severe colitis presenting with watery diarrhea. - Acute interstitial nephritis: kidney inflammation causing reduced urine output. - Hypomagnesemia: low magnesium levels leading to muscle cramps or arrhythmias. - Stevens‑Johnson syndrome: severe skin reactions with blistering and detachment. - Liver enzyme elevation: increased ALT/AST indicating hepatic stress.

When prescribing Omeprazol Azevedos, consider the following precautions: - Assess renal function: adjust use in patients with severe kidney impairment. - Evaluate hepatic status: use with caution in moderate to severe liver disease. - Monitor long‑term use: prolonged therapy may increase fracture risk. - Review concomitant medications: may affect absorption of drugs requiring acidic pH. - Pregnancy and lactation: weigh benefits against potential risks. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Omeprazol Azevedos can affect the plasma concentrations of several co‑administered medicines.

Major Interactions (Avoid): - Clopidogrel: reduced antiplatelet effect, increasing cardiovascular event risk. - Atazanavir: markedly decreased antiviral exposure, compromising HIV treatment. - Dasatinib: lowered drug levels, potentially reducing cancer therapy efficacy.

Moderate Interactions (Monitor Closely): - Warfarin: possible increase in INR, requiring more frequent coagulation monitoring. - Phenytoin: altered serum levels, may need dose adjustment. - Methotrexate: increased exposure, especially at high doses, necessitating renal function checks.