Europe — EMA
Olynth (Xylometazoline Hydrochloride)
Xylometazoline Hydrochloride, the active ingredient in Olynth, is an alpha‑adrenergic nasal decongestant presented as a topical nasal spray for intranasal use.
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What is Xylometazoline Hydrochloride?
Xylometazoline Hydrochloride, the active ingredient in Olynth, is an alpha‑adrenergic nasal decongestant presented as a topical nasal spray for intranasal use. It relieves nasal congestion associated with common colds, sinusitis and allergic rhinitis in adults and children.
GNH USA supplies Olynth as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Xylometazoline Hydrochloride used for?
Olynth is a nasal decongestant that acts on the upper‑respiratory tract to reduce swelling of nasal mucosa. - Common cold: temporary relief of nasal blockage and stuffiness. - Acute sinusitis: helps clear nasal passages and improve airflow. - Allergic rhinitis: reduces nasal congestion caused by seasonal allergens. - Upper‑respiratory viral infection: eases breathing discomfort during the illness.
What are the side effects of Xylometazoline Hydrochloride?
Side effects are generally mild and related to local irritation of the nasal mucosa.
Common Side Effects: - Burning or stinging sensation in the nose. - Nasal dryness or crusting. - Sneezing shortly after application. - Mild headache. - Transient epistaxis (nosebleed).
Serious or Rare Side Effects: - Persistent nasal irritation or ulceration. - Severe or prolonged nosebleeds. - Allergic reaction with swelling of the face, lips or throat. - Hypertensive crisis in patients sensitive to systemic alpha‑adrenergic effects.
What precautions apply to Xylometazoline Hydrochloride?
Before using Olynth, consider the following safety measures: - Age restriction: not recommended for children under 6 years without medical advice. - Duration of use: limit to 3‑5 days to avoid rebound congestion. - Pre‑existing conditions: use cautiously in patients with hypertension, heart disease, diabetes, thyroid disorders, or glaucoma. - Concomitant nasal medications: avoid using other topical decongestants simultaneously. - Pregnancy & lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.
What does Xylometazoline Hydrochloride interact with?
Xylometazoline may interact with other medicines that affect vascular tone or blood pressure.
Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs) combined with - Beta‑beta
Moderate : - Oral antihypertensive drugs. - Nasal corticosteroids. - Other topical nasal decongestants. - Herbal ",
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