Europe — EMA
Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo (Olmesartan Medoxomil, Hydrochlorothiazide)
GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo (Olmesartan), an ARB for hypertension and related cardiovascular conditions.
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What is Olmesartan Medoxomil, Hydrochlorothiazide?
Olmesartan medoxil, the active ingredient in Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo, is an angiotensin II receptor blocker presented as a tablet for oral use. It treats hypertension, often in combination with a thiazide diuretic, and is indicated for adults. GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
What is Olmesartan Medoxomil, Hydrochlorothiazide used for?
Olmesartan medoxil, combined with hydrochlorothiazide, is used in cardiovascular therapy to control blood pressure.
- Hypertension: lowers systolic and diastolic blood pressure in patients with primary hypertension. - Heart failure adjunct: assists in fluid management when used with other heart‑failure therapies. - Diabetic nephropathy risk reduction: helps delay progression of kidney damage associated with diabetes by controlling hypertension. - Stroke prevention: contributes to reduced risk of stroke in patients with high blood pressure. - Chronic kidney disease support: aids in blood‑pressure control for patients with mild to moderate chronic kidney disease.
What are the side effects of Olmesartan Medoxomil, Hydrochlorothiazide?
Adverse reactions may vary in frequency and severity.
Common Side Effects: - Dizziness or light‑headedness - Headache - Fatigue - Increased urination - Electrolyte disturbances (e.g., low potassium) - Mild gastrointestinal discomfort
Serious or Rare Side Effects: - Severe hypotension - Acute kidney injury - Hyperkalemia or severe electrolyte imbalance - Angio‑edema involving face, lips or airway - Liver function abnormalities - Blood cell disorders such as neutropenia
What precautions apply to Olmesartan Medoxomil, Hydrochlorothiazide?
When prescribing Olmesartan Medoxomilo + Hidroclorotiazida, clinicians should consider several safety aspects.
- Renal function: assess baseline creatinine and monitor periodically. - Electrolyte balance: check serum potassium and sodium levels regularly. - Pregnancy: contraindicated in the second and third trimesters; avoid use. - Concomitant drugs: review for potential interactions that affect potassium or renal function. - Hypersensitivity: discontinue if angio‑edema or severe rash develops. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.
What does Olmesartan Medoxomil, Hydrochlorothiazide interact with?
Olmesartan Medoxomilo + Hidroclorotiazida may interact with several medicines, requiring clinical awareness.
Major Interactions (Avoid): - Potassium‑sparing diuretics or supplements: risk of hyperkalemia. - Aliskiren (in diabetic patients): increased risk of renal impairment and hypotension. - NSAIDs (high‑dose or chronic use): may blunt antihypertensive effect and affect renal function.
Moderate Interactions (Monitor Closely): - Lithium: possible increase in lithium levels. - Antidiabetic agents: enhanced glucose‑lowering effect, monitor blood sugar. - Other antihypertensives: additive blood‑pressure lowering, watch for hypotension.
Frequently asked questions
What is Olmesartan Medoxomilo + Hidroclorotiazida used for?+
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Product details
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