GNH USA

Europe — EMA

Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo (Olmesartan Medoxomil, Hydrochlorothiazide)

GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo (Olmesartan), an ARB for hypertension and related cardiovascular conditions.

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What is Olmesartan Medoxomil, Hydrochlorothiazide?

Olmesartan medoxil, the active ingredient in Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo, is an angiotensin II receptor blocker presented as a tablet for oral use. It treats hypertension, often in combination with a thiazide diuretic, and is indicated for adults. GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

GNH USA supplies Olmesartan Medoxomilo + Hidroclorotiazida Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.

What is Olmesartan Medoxomil, Hydrochlorothiazide used for?

Olmesartan medoxil, combined with hydrochlorothiazide, is used in cardiovascular therapy to control blood pressure.

- Hypertension: lowers systolic and diastolic blood pressure in patients with primary hypertension. - Heart failure adjunct: assists in fluid management when used with other heart‑failure therapies. - Diabetic nephropathy risk reduction: helps delay progression of kidney damage associated with diabetes by controlling hypertension. - Stroke prevention: contributes to reduced risk of stroke in patients with high blood pressure. - Chronic kidney disease support: aids in blood‑pressure control for patients with mild to moderate chronic kidney disease.

What are the side effects of Olmesartan Medoxomil, Hydrochlorothiazide?

Adverse reactions may vary in frequency and severity.

Common Side Effects: - Dizziness or light‑headedness - Headache - Fatigue - Increased urination - Electrolyte disturbances (e.g., low potassium) - Mild gastrointestinal discomfort

Serious or Rare Side Effects: - Severe hypotension - Acute kidney injury - Hyperkalemia or severe electrolyte imbalance - Angio‑edema involving face, lips or airway - Liver function abnormalities - Blood cell disorders such as neutropenia

What precautions apply to Olmesartan Medoxomil, Hydrochlorothiazide?

When prescribing Olmesartan Medoxomilo + Hidroclorotiazida, clinicians should consider several safety aspects.

- Renal function: assess baseline creatinine and monitor periodically. - Electrolyte balance: check serum potassium and sodium levels regularly. - Pregnancy: contraindicated in the second and third trimesters; avoid use. - Concomitant drugs: review for potential interactions that affect potassium or renal function. - Hypersensitivity: discontinue if angio‑edema or severe rash develops. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Olmesartan Medoxomil, Hydrochlorothiazide interact with?

Olmesartan Medoxomilo + Hidroclorotiazida may interact with several medicines, requiring clinical awareness.

Major Interactions (Avoid): - Potassium‑sparing diuretics or supplements: risk of hyperkalemia. - Aliskiren (in diabetic patients): increased risk of renal impairment and hypotension. - NSAIDs (high‑dose or chronic use): may blunt antihypertensive effect and affect renal function.

Moderate Interactions (Monitor Closely): - Lithium: possible increase in lithium levels. - Antidiabetic agents: enhanced glucose‑lowering effect, monitor blood sugar. - Other antihypertensives: additive blood‑pressure lowering, watch for hypotension.

Frequently asked questions

What is Olmesartan Medoxomilo + Hidroclorotiazida used for?+
Olmesartan Medoxomilo + Hidroclorotiazida is a fixed‑dose combination of an angiotensin II receptor blocker and a thiazide diuretic. It is prescribed to lower high blood pressure in adults, often when monotherapy does not achieve target levels. Controlling hypertension helps reduce the risk of cardiovascular events such as stroke and heart attack.
How does olmesartan medoxil work?+
Olmesartan medoxil blocks the AT1 receptor for angiotensin II, preventing vasoconstriction and aldosterone‑mediated sodium retention. Hydrochlorothiazide acts on the distal convoluted tubule to inhibit sodium‑chloride reabsorption, increasing urine output. Together they lower peripheral resistance and plasma volume, producing an additive antihypertensive effect.
What is the usual dose of this medication?+
The dosage of Olmesartan Medoxomilo + Hidroclorotiazida is individualized by the prescribing clinician based on the patient’s blood‑pressure readings, renal function, and overall health status. The prescriber determines the appropriate strength and frequency according to clinical guidelines.
Is this product safe during pregnancy or breastfeeding?+
Olmesartan Medoxomilo + Hidroclorotiazida is contraindicated in the second and third trimesters of pregnancy because of potential fetal toxicity. Use during the first trimester should be avoided unless clearly needed. Limited data are available for breastfeeding; therefore, it is generally not recommended without medical supervision.
How do I order Olmesartan Medoxomilo + Hidroclorotiazida from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does this combination compare with other antihypertensive options?+
Compared with single‑agent ARBs or ACE inhibitors, the Olmesartan‑hydrochlorothiazide combo offers an added diuretic effect, often achieving target blood pressure more rapidly. It may be preferred when patients need both vasodilation and volume reduction, reducing the need for multiple separate pills.
What are the recommended storage conditions for this product?+
Store the tablets at ambient temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.
How is Olmesartan Medoxomilo + Hidroclorotiazida administered?+
The medication is taken orally, usually once daily, with or without food, as directed by the prescribing healthcare professional. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.
What are the most serious risks associated with this medication?+
Serious adverse events include severe hypotension, acute kidney injury, hyperkalemia, angio‑edema and liver function abnormalities. Patients should seek immediate medical attention if they experience swelling of the face or throat, sudden dizziness, or marked changes in urine output.
Who should not use this medication?+
Individuals with known hypersensitivity to olmesartan, hydrochlorothiazide or any component of the formulation should avoid it. It is also contraindicated in patients with severe renal impairment, hyperkalemia, or those who are pregnant in the second or third trimester.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Olmesartan Medoxomil, Hydrochlorothiazide
Route
Oral Use
Manufacturer
Generis Farmacêutica, S.A.
Origin
EU

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