Europe — EMA
Olmesartan Aurobindo Pharma (Malta) (Olmesartan Medoxomil)
GNH USA supplies Olmesartan Aurobindo Pharma (Malta) (Olmesatran), a angiotensin II receptor blocker for hypertension and heart‑failure management.
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What is Olmesartan Medoxomil?
Olmesartan medoxil, the active ingredient in Olmesartan Aurobindo Pharma (Malta), is an angiotensin II receptor blocker presented as a tablet for oral use. It is used to treat high blood pressure in adults.
GNH USA supplies Olmesartan Aurobindo Pharma (Malta) as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Olmesartan Medoxomil used for?
Olmesartan medoxil is indicated for hypertension management, acting on the renin‑angiotensin system to lower blood pressure. - Hypertension: Helps reduce systolic and diastolic blood pressure, decreasing cardiovascular risk. - Heart failure: Used as part of combination therapy to improve outcomes in patients with reduced ejection fraction. - Diabetic nephropathy: Provides renal protection by lowering intraglomerular pressure in patients with type 2 diabetes.
What are the side effects of Olmesartan Medoxomil?
Adverse reactions to olmesartan may vary in frequency and severity.
Common Side Effects: - Dizziness - Headache - Fatigue - Nasal congestion - Diarrhea
Serious or Rare Side Effects: - Angio‑edema - Severe hypotension - Acute kidney injury - Hyperkalemia - Liver enzyme elevations
What precautions apply to Olmesartan Medoxomil?
When prescribing olmesartan, clinicians should consider several safety aspects. - Pregnancy: Contra‑indicated in the second and third trimesters due to risk of fetal toxicity. - Renal impairment: Monitor kidney function and adjust therapy as needed. - Hyperkalemia risk: Check serum potassium, especially when combined with potassium‑sparing diuretics. - Drug‑induced hypotension: Advise patients to rise slowly from sitting or lying positions. - Store at below 25°C: keep in the original packaging for protect against moisture.
What does Olmesartan Medoxomil interact with?
Olmesartan can interact with several other medicines, requiring attention to avoid reduced efficacy or increased toxicity.
Major Interactions (Avoid): - Aliskiren: Co‑administration in diabetic patients is prohibited. - Potassium‑sparing diuretics: May cause dangerous hyper‑kalemia. - NSAIDs: Can blunt antihypertensive effect and impair renal function.
Moderate Interactions (Monitor Closely): - ACE inhibitors: Combined use raises risk of hypotension, hyper‑kalemia, and renal dysfunction. - Lithium: May increase lithium levels and risk of toxicity. - Rifampicin: May reduce olmesartan plasma concentrations.
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