Europe — EMA
Olmesartan/Amlodipine Sandoz (Olmesartan Medoxomil, Amlodipine)
Olmesartan medoxyl, the active ingredient in Olmesartan/Amlodipine Sandoz, is an angiotensin II receptor blocker presented as a tablet for oral use.
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What is Olmesartan Medoxomil, Amlodipine?
Olmesartan medoxyl, the active ingredient in Olmesartan/Amlodipine Sandoz, is an angiotensin II receptor blocker presented as a tablet for oral use. It treats hypertension, often in combination with a calcium‑channel blocker, and is intended for adult patients. GNH USA supplies Olmesartan/Amlodipine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
GNH USA supplies Olmesartan/Amlodipine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and pharmacies worldwide.
What is Olmesartan Medoxomil, Amlodipine used for?
Olmesartan/Amlodipine combines a renin‑angiotensin system blocker with a calcium‑channel blocker to manage high blood pressure.
- Hypertension: improves blood pressure control when monotherapy is insufficient. - Chronic kidney disease with hypertension: slows progression by reducing intraglomerular pressure. - Cardiovascular risk reduction in patients with hypertension and additional risk factors: contributes to lower incidence of stroke and myocardial infarction.
What are the side effects of Olmesartan Medoxomil, Amlodipine?
Side effects reported with the combination reflect the profile of each component.
Common Side Effects: - Peripheral edema - Headache - Dizziness - Flushing - Fatigue - Nasal congestion
Serious or Rare Side Effects: - Angio‑edema - Severe hypotension - Acute kidney injury - Hepatic enzyme elevation - Myocardial infarction in susceptible patients - Hyperkalemia
What precautions apply to Olmesartan Medoxomil, Amlodipine?
When prescribing Olmesartan/Amlodipine, clinicians should consider several safety aspects.
- Renal impairment: dose may need adjustment and renal function monitored. - Hepatic impairment: use with caution; monitor liver enzymes. - Electrolyte disturbances: watch for hyperkalemia, especially with potassium‑sparing diuretics. - Pregnancy: contraindicated in the second and third trimesters due to fetal toxicity. - Elderly patients: start at lower dose to reduce risk of orthostatic hypotension. - Store at ambient temperature: keep in original packaging and protect from moisture.
What does Olmesartan Medoxomil, Amlodipine interact with?
Olmesartan/Amlodine
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