GNH USA

Europe — EMA

Olmesartan/Amlodipine Eg (Olmesartan Medoxomil, Amlodipine)

GNH USA supplies Olmesartan/Amlodipine EG (Olmesartan/amlodipine), a antihypertensive for hypertension.

Olmesartan Medoxomil, Amlodipine

Request sourcing

1
Pack/s

What is Olmesartan Medoxomil, Amlodipine?

Olmesartan medoxomil / amlodipine, the active ingredient in Olmesartan/Amlodipine EG, is an angiotensin II receptor blocker combined with a calcium channel blocker presented as an oral tablet for systemic use. It is indicated for the management of hypertension in adult patients, offering complementary mechanisms to lower blood pressure.

GNH USA supplies Olmesartan/Amlodipine EG as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for regulated markets.

What is Olmesartan Medoxomil, Amlodipine used for?

Olmesartan/Amlodipine is used in the cardiovascular therapeutic area to control elevated blood pressure.

Hypertension: lowers systolic and diastolic pressure in patients with primary hypertension. Essential hypertension: provides additive blood‑pressure reduction when monotherapy does not achieve target levels. Uncontrolled hypertension: employed as combination therapy to reach recommended blood‑pressure goals.

What are the side effects of Olmesartan Medoxomil, Amlodipine?

Common Side Effects: - Dizziness or light‑headedness - Headache - Peripheral edema, especially of the ankles - Flushing or warmth sensation - Fatigue or tiredness - Palpitations or mild tachycardia

Serious or Rare Side Effects: - Angioedema involving face, lips or throat - Severe hypotension with syncope - Hepatic enzyme elevation or liver injury - Myocardial infarction or acute coronary syndrome - Life‑threatening arrhythmias - Severe allergic reactions such as Stevens‑Johnson syndrome

What precautions apply to Olmesartan Medoxomil, Amlodipine?

Olmesartan/Amlodipine should be used with clinical judgment and monitoring. - Pregnancy: Category D; avoid unless benefits outweigh risks. - Renal impairment: monitor kidney function and adjust therapy as needed. - Hepatic impairment: use cautiously; liver enzymes should be checked periodically. - Concomitant potassium‑sparing diuretics or supplements: risk of hyperkalemia; monitor serum potassium. - Severe aortic stenosis or cardiogenic shock: contraindicated due to risk of profound hypotension. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

What does Olmesartan Medoxomil, Amlodipine interact with?

Olmesartan/Amlodipine may interact with several medicines that affect blood pressure or drug metabolism.

Major Interactions (Avoid): - Potassium‑sparing diuretics (e.g., spironolactone): increase risk of hyperkalemia. - Aliskiren in diabetic patients: heightened renal adverse events. - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): raise amlodipine plasma levels. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may blunt antihypertensive effect. - Lithium: elevated lithium concentrations and toxicity.

Moderate Interactions (Monitor Closely): - Rifampin or other CYP3A4 inducers: may reduce amlodipine exposure. - Carbamazepine: decreases amlodipine concentrations. - ACE inhibitors or other renin‑angiotensin system blockers: additive hypotensive effect. - Loop or thiazide diuretics: enhanced blood‑pressure lowering. - Beta‑blockers: potential for excessive bradycardia or hypotension.

Frequently asked questions

What is Olmesartan/Amlodipine EG used for?+
Olmesartan/Amlodipine EG is a fixed‑dose combination of an angiotensin II receptor blocker and a calcium‑channel blocker. It is prescribed to lower elevated blood pressure in adults with primary (essential) hypertension, often when a single agent does not achieve target levels.
How does Olmesartan medoxomil / amlodipine work?+
Olmesartan medoxomil blocks AT1 receptors, preventing angiotensin II‑mediated vasoconstriction and aldosterone release. Amlodipine inhibits L‑type calcium channels in vascular smooth muscle, causing arterial dilation. Together they reduce peripheral resistance and cardiac afterload, producing a sustained antihypertensive effect.
What is the usual dose of Olmesartan/Amlodipine EG?+
The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s blood‑pressure profile, renal function, and concomitant therapies. The prescriber selects the appropriate strength and frequency according to clinical guidelines.
Is Olmesartan/Amlodipine EG safe during pregnancy or breastfeeding?+
Olmesartan/Amlodipine EG is classified as Pregnancy Category D, indicating evidence of risk to the fetus. It should be avoided during pregnancy unless the potential benefit justifies the risk. Limited data are available for breastfeeding; the product should be used only if the potential benefit outweighs possible harm to the infant.
How do I order Olmesartan/Amlodipine EG from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Olmesartan/Amlodipine compare with other antihypertensive options?+
Compared with monotherapy, the combination offers dual mechanisms—AT1‑receptor blockade and calcium‑channel inhibition—resulting in greater blood‑pressure reduction and improved adherence due to a single tablet. It is often preferred over separate pills when tighter control is needed, but individual agents may be chosen based on patient‑specific factors such as comorbidities.
What are the storage and handling requirements for Olmesartan/Amlodipine EG?+
Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture, heat and direct sunlight. Do not use if the packaging is damaged or if tablets appear discolored.
How is Olmesartan/Amlodipine EG administered?+
Olmesartan/Amlodipine EG is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the prescriber’s instructions regarding timing and any dose adjustments.
What are the most serious risks associated with Olmesartan/Amlodipine EG?+
Serious adverse events include angioedema, severe hypotension, hepatic injury, myocardial infarction, and life‑threatening arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face or throat, sudden dizziness, chest pain, or signs of liver dysfunction.
Who should not use Olmesartan/Amlodipine EG?+
The combination is contraindicated in patients with known hypersensitivity to either component, severe aortic stenosis, cardiogenic shock, or those who are pregnant unless the benefit outweighs the risk. Caution is also advised for individuals with significant renal or hepatic impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Olmesartan Medoxomil, Amlodipine
Route
Oral Use
Manufacturer
Eurogenerics N.V./S.A.
Origin
EU

Related products

Albis

Albis

Olmesartan Medoxomil, Amlodipine

Laboratorios Alter, S.A.
EU
Almacor Duo

Almacor Duo

Olmesartan Medoxomil, Amlodipine

Antibiotice Sa
EU
Alsamod

Alsamod

Olmesartan Medoxomil, Amlodipine

Krka, D.D., Novo Mesto
EU
Amelior

Amelior

Olmesartan Medoxomil, Amlodipine

Menarini International Operations Luxembourg S.A.
EU