GNH USA

Europe — EMA

Olimel

GNH USA supplies Olimel (amino acids), a supplement for parenteral nutrition in patients unable to receive enteral feeding. Request a quote for supply.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredient in Olimel, is a nutritional supplement presented as an intravenous solution for intravenous use. It supplies a balanced mixture of essential and non‑essential amino acids to support protein synthesis, maintain nitrogen balance, and provide caloric support in patients who cannot receive enteral feeding.

GNH USA supplies Olimel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics and research institutions worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel is used in parenteral nutrition to provide amino acids for patients who cannot receive enteral feeding.

- Inability to tolerate enteral feeding: supplies essential amino acids to maintain protein synthesis and nitrogen balance. - Critical illness: supports metabolic demands and prevents catabolism in intensive‑care patients. - Postoperative recovery: aids tissue repair and wound healing by providing building blocks for new protein.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions may occur with intravenous amino‑acid solutions. Monitoring during infusion is recommended.

Common Side Effects: - Infusion site phlebitis or erythema. - Mild hypernatremia or electrolyte shift. - Transient fever or chills. - Nausea or mild gastrointestinal discomfort. - Headache. - Mild metabolic alkalosis.

Serious or Rare Side Effects: - Anaphylactic or severe allergic reaction. - Severe electrolyte imbalance (hyperkalemia, hypocalcemia). - Acute renal dysfunction or oliguria. - Hepatic dysfunction with elevated transaminases. - Severe hyperammonemia. - Sepsis related to contaminated infusion.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel, consider the following safety measures.

- Assess renal function: monitor creatinine and adjust infusion rate as needed. - Monitor electrolytes: watch serum sodium, potassium, calcium, and phosphate levels. - Check for allergies: ensure no known hypersensitivity to any amino acid component. - Use aseptic technique: prepare and administer under sterile conditions to prevent contamination. - Avoid in patients with inborn errors of amino‑acid metabolism: contraindicated in such metabolic disorders. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Potential drug interactions should be evaluated before initiating therapy.

Major Interactions (Avoid): - Concurrent high‑dose amino‑acid solutions: risk of amino‑acid overload and metabolic disturbances. - Incompatible IV fluids containing calcium: may cause precipitation and catheter blockage.

Moderate Interactions (Monitor Closely): - Loop diuretics: may increase loss of electrolytes supplied by the solution. - Insulin therapy: can alter amino‑acid uptake and glucose metabolism. - Renal replacement therapy: may remove administered amino acids, reducing efficacy. - High‑dose corticosteroids: can affect protein catabolism and nitrogen balance. - Certain antiepileptic drugs: may interfere with amino‑acid metabolism.

Frequently asked questions

What is Olimel used for?+
Olimel is an intravenous amino‑acid solution used as part of parenteral nutrition. It provides essential and non‑essential amino acids to patients who cannot receive enteral feeding, helping to maintain protein synthesis, nitrogen balance, and overall metabolic support during critical illness, surgery, or severe malnutrition.
How does the amino‑acid blend in Olimel work?+
The amino‑acid blend in Olimel supplies the building blocks required for protein synthesis. Once infused, the amino acids are taken up by cells, activating the mTOR pathway and other translational mechanisms that promote muscle maintenance, tissue repair, and energy production, while also supporting nitrogen balance in the body.
What is the usual dose of Olimel?+
The dose of Olimel is individualized. A qualified prescriber determines the amount, concentration, and infusion rate based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional requirements. No fixed regimen is provided in public documents.
Is Olimel safe to use during pregnancy or breastfeeding?+
Safety data for Olimel in pregnancy and lactation are limited. Because it is a parenteral nutrition product, it should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Olimel from GNH USA?+
To order Olimel, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and the necessary import documentation.
How does Olimel compare with other parenteral nutrition products?+
Olimel offers a comprehensive amino‑acid profile that includes both essential and non‑essential amino acids, similar to other high‑quality parenteral nutrition solutions. Compared with products that contain only essential amino acids, Olimel may provide broader metabolic support, but the choice depends on the patient’s specific clinical needs and physician preference.
What are the storage requirements for Olimel?+
Olimel must be stored at 2‑8 °C. Keep the solution refrigerated, protect it from light, and avoid freezing or shaking the container. Follow the manufacturer’s labeling for any additional handling instructions to maintain product stability.
How is Olimel administered?+
Olimel is administered intravenously, typically through a central venous catheter or a peripheral line, depending on the prescribed concentration and infusion rate. The infusion is performed under aseptic conditions, and the rate is adjusted according to the patient’s metabolic needs and clinical monitoring.
What are the most serious risks associated with Olimel?+
Serious risks include severe allergic reactions such as anaphylaxis, significant electrolyte disturbances, acute renal or hepatic dysfunction, and hyperammonemia. Continuous monitoring of vital signs, renal function, liver enzymes, and electrolyte levels is essential to detect and manage these potential complications promptly.
Who should not receive Olimel?+
Olimel should be avoided in patients with known hypersensitivity to any of its amino‑acid components, those with inborn errors of amino‑acid metabolism, and individuals in whom parenteral nutrition is contraindicated due to severe fluid overload or uncontrolled metabolic disorders.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Deutschland Gmbh
Origin
EU