GNH USA

Europe — EMA

Olimel Perifer N4e

GNH USA supplies Olimel Perifer N4e (amino acid blend), a nutritional supplement for malnutrition and post‑operative recovery.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel Perifer N4e, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel Perifer N4e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel Perifer N4e provides amino acid supplementation that supports several clinical situations where protein intake is compromised. - Malnutrition: Helps restore nitrogen balance and supports tissue repair. - Post‑operative recovery: Contributes to wound healing and muscle preservation. - Chronic kidney disease (conservative management): Supplies essential amino acids while limiting nitrogen load. - Severe burns: Assists in meeting heightened protein requirements for healing. - Long‑term parenteral nutrition: Provides a balanced amino acid profile for patients unable to use the gastrointestinal tract.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid mixtures are generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild to moderate gastrointestinal discomfort. - Vomiting: occasional episodes, especially if administered rapidly. - Diarrhea: loose stools in some patients. - Abdominal cramping: transient discomfort after ingestion. - Metallic taste: perception of a metallic flavor in the mouth. - Headache: mild headache reported by some users.

Serious or Rare Side Effects: - Hyperammonemia: elevated blood ammonia levels, particularly in severe liver dysfunction. - Allergic reaction: rash, itching, or urticaria. - Anaphylaxis: rare, severe systemic hypersensitivity. - Metabolic acidosis: rare disturbance of acid‑base balance. - Electrolyte imbalance: abnormal serum potassium or calcium levels. - Renal impairment worsening: potential increase in serum creatinine in susceptible patients.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Olimel Perifer N4e, consider the following safety measures: - Renal function: assess baseline kidney parameters before initiating therapy. - Hepatic function: monitor liver enzymes in patients with known liver disease. - Electrolyte status: check serum electrolytes regularly during prolonged use. - Nutritional assessment: ensure the product fits within the overall dietary plan. - Concomitant nutrition: avoid excessive protein intake from other sources. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid mixtures can interact with certain medications and nutrients.

Major Interactions (Avoid): - Levodopa: may reduce absorption of levodopa, diminishing its effectiveness. - MAO inhibitors: risk of hypertensive crisis when combined with high‑tyrosine content. - Thyroid hormone replacement: can interfere with absorption of levothyroxine.

Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., phenytoin): may alter plasma amino acid levels. - Diuretics: can affect electrolyte balance when combined with high‑sodium formulations. - Iron supplements: compete for intestinal absorption sites, reducing iron uptake.

Frequently asked questions

What is Olimel Perifer N4e used for?+
Olimel Perifer N4e is an oral amino acid powder designed to provide essential and non‑essential amino acids for patients who need nutritional supplementation, such as those with malnutrition, post‑operative recovery needs, chronic kidney disease, severe burns, or requiring long‑term parenteral nutrition.
How does the amino acid blend in Olimel Perifer N4e work?+
The blend supplies the building blocks required for protein synthesis, helping to maintain plasma amino acid levels, support tissue repair, and preserve nitrogen balance. These amino acids are directly utilized by cells in metabolic pathways that produce enzymes, structural proteins, and other vital molecules.
What is the usual dose of Olimel Perifer N4e?+
The prescribed dose of Olimel Perifer N4e is determined by the treating clinician based on the patient’s nutritional status, underlying condition, and overall treatment plan. Dosage may be adjusted according to laboratory results and clinical response.
Is Olimel Perifer N4e safe during pregnancy or breastfeeding?+
Safety data for Olimel Perifer N4e in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Olimel Perifer N4e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Olimel Perifer N4e compare with other amino acid products?+
Olimel Perifer N4e offers a comprehensive profile of ten amino acids, providing a balanced mixture that may be broader than single‑amino‑acid formulations. Compared with other multi‑amino‑acid powders, it follows EU‑quality standards and is intended for oral supplementation in a range of clinical settings.
What are the storage and handling requirements for Olimel Perifer N4e?+
Store the powder at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme temperatures to maintain stability and potency.
How is Olimel Perifer N4e administered?+
The product is supplied as a powder that is reconstituted with water or a suitable liquid according to the prescribing information, then taken orally. Administration instructions, including mixing volume and timing, should be followed as directed by the healthcare professional.
What are the most serious risks associated with Olimel Perifer N4e?+
Serious risks include hyperammonemia, allergic reactions such as rash or anaphylaxis, metabolic acidosis, and potential worsening of renal impairment. Patients should be monitored for these events, especially if they have pre‑existing liver or kidney disease.
Who should not use Olimel Perifer N4e?+
Individuals with known hypersensitivity to any of the listed amino acids, those with severe liver dysfunction prone to hyperammonemia, or patients for whom a high protein load is contraindicated should avoid using this product unless specifically directed by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Medical Ab
Origin
EU