GNH USA

Europe — EMA

Olimel Peri N4e

GNH USA supplies Olimel Peri N4e (Valine et al.), a dietary supplement for metabolic support in post‑operative, renal and malnutrition care.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel Peri N4e, is a mixture of essential and non‑essential amino acids presented as a dietary supplement for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional support. GNH USA supplies Olimel Peri N4e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel Peri N4e provides amino acid supplementation for conditions where protein turnover is increased. - Post‑operative recovery: helps maintain nitrogen balance during wound healing. - Chronic kidney disease: supports dietary protein needs while managing uremic restrictions. - Severe malnutrition: contributes to rebuilding lean body mass in undernourished patients.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid supplementation is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Diarrhea: loose stools, usually transient. - Abdominal discomfort: cramping or bloating. - Metallic taste: temporary alteration in mouthfeel. - Headache: mild, self‑limiting. - Rash: mild skin erythema.

Serious or Rare Side Effects: - Hyperammonemia: elevated blood ammonia in susceptible individuals. - Allergic reaction: hives, swelling, or anaphylaxis. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe gastrointestinal bleeding: uncommon but serious. - Renal impairment exacerbation: potential worsening in patients with existing kidney disease. - Hepatotoxicity: rare liver enzyme elevation.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Olimel Peri N4e, consider patient‑specific factors and monitor relevant clinical parameters. - Renal function: assess baseline creatinine and adjust if needed. - Hepatic function: evaluate liver enzymes before initiating therapy. - Metabolic status: monitor ammonia levels in patients prone to hyperammonemia. - Allergies: verify no known hypersensitivity to any listed amino acids. - Concomitant nutrition: coordinate with overall dietary plan to avoid excess protein intake. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid mixtures can influence the absorption or metabolism of certain drugs.

Major Interactions (Avoid): - Levodopa: may compete for transport across the intestinal wall, reducing efficacy. - Anticonvulsants (e.g., valproate): can alter plasma amino acid levels, affecting seizure control.

Moderate Interactions (Monitor Closely): - Thyroid hormones: high amino acid load may affect hormone binding proteins. - Insulin and oral hypoglycemics: amino acids can modify glucose metabolism, requiring dose adjustments. - Antibiotics (e.g., tetracycline): chelation may reduce antibiotic absorption. - Warfarin: protein intake changes can influence INR stability. - Diuretics: altered electrolyte balance may affect renal clearance of amino acids.

Frequently asked questions

What is Olimel Peri N4e used for?+
Olimel Peri N4e is an oral amino‑acid blend intended to supplement protein and nitrogen needs in patients with increased catabolism, such as after surgery, in chronic kidney disease, or severe malnutrition. It helps support tissue repair and metabolic balance when dietary intake alone may be insufficient.
How does the Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin blend work?+
The blend provides essential and non‑essential amino acids that act as building blocks for protein synthesis, stimulate the mTOR pathway, and serve as nitrogen donors for gluconeogenesis. This supports muscle maintenance, wound healing, and overall metabolic homeostasis in catabolic states.
What is the usual dose of Olimel Peri N4e?+
The prescribed dose of Olimel Peri N4e is determined by the treating clinician based on the individual’s nutritional status, underlying condition, and renal or hepatic function. Healthcare professionals tailor the amount to meet each patient’s specific protein and amino‑acid requirements.
Is Olimel Peri N4e safe during pregnancy or breastfeeding?+
Safety data for this amino‑acid blend in pregnancy or lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Olimel Peri N4e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and required import documentation.
How does Olimel Peri N4e compare with other nutritional supplements?+
Compared with single‑amino‑acid products, Olimel Peri N4e offers a balanced mixture of ten amino acids, providing a broader substrate profile for protein synthesis. It differs from generic protein powders by delivering precise, pharmaceutical‑grade concentrations suitable for clinical nutrition protocols.
What are the storage and handling requirements for Olimel Peri N4e?+
Store the product at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme temperature fluctuations to maintain stability and potency.
How is Olimel Peri N4e administered?+
Olimel Peri N4e is taken orally, usually dissolved in water or mixed with a suitable beverage as directed by the healthcare provider. It should be consumed according to the prescribed schedule, typically with meals to improve tolerance.
What are the most serious risks associated with Olimel Peri N4e?+
Serious risks, though rare, include hyperammonemia, severe allergic reactions such as anaphylaxis, metabolic acidosis, and potential worsening of existing renal or hepatic impairment. Patients should be monitored for any signs of these conditions, especially during the initial treatment period.
Who should not use Olimel Peri N4e?+
Individuals with known hypersensitivity to any of the listed amino acids, those with uncontrolled hyperammonemia, severe hepatic failure, or those on medications that may interact adversely (e.g., levodopa) should avoid using this product unless closely supervised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Hellas
Origin
EU