GNH USA

Europe — EMA

Olimel Peri N4e

GNH USA supplies Olimel Peri N4e (Valine et al.), a nutritional amino acid supplement for post‑operative, renal and trauma care.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel Peri N4e, is a mixture of essential and non‑essential amino acids presented as a nutritional supplement for oral use. It supports metabolic functions and protein synthesis in patients requiring additional amino acid intake.

GNH USA supplies Olimel Peri N4e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel Peri N4e provides amino acid supplementation for conditions where protein turnover is increased. - Post‑operative recovery: helps maintain nitrogen balance during tissue repair. - Chronic kidney disease: supports nutritional status when dietary protein is restricted. - Severe burns or trauma: aids in rebuilding muscle protein loss. - Malnutrition in elderly patients: contributes to overall protein intake. - Metabolic disorders affecting amino acid utilization: assists in correcting deficiencies.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid mixtures are generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild gastrointestinal discomfort. - Diarrhea: loose stools, usually transient. - Abdominal bloating: feeling of fullness or gas. - Metallic taste: temporary alteration in taste perception. - Headache: mild to moderate intensity. - Skin redness at oral mucosa: mild irritation.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Hyperammonemia: elevated blood ammonia levels, especially in severe liver disease. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe electrolyte imbalance: uncommon but possible with high‑dose regimens. - Renal function deterioration: in patients with pre‑existing kidney impairment. - Unexplained fever: persistent temperature rise without infection.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Before prescribing Olimel Peri N4e, consider patient‑specific factors and monitor relevant clinical parameters. - Renal impairment: adjust dosage and monitor kidney function tests. - Hepatic disease: watch for signs of hyperammonemia. - Pregnancy and lactation: evaluate risk‑benefit ratio; use only if clearly needed. - Concomitant nutrition therapy: coordinate with dietitian to avoid excess protein. - Pediatric use: limit to specialist supervision and appropriate dosing. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid supplements can influence the pharmacokinetics of certain medicines.

Major Interactions (Avoid): - Levodopa: competition for transport may reduce central availability. - Anticonvulsants (e.g., valproate): may alter plasma amino acid levels.

Moderate Interactions (Monitor Closely): - Thyroid hormones: high amino acid load can affect absorption. - Iron supplements: concurrent intake may decrease iron absorption. - Antibiotics (tetracyclines, quinolones): calcium in the formulation can bind and reduce efficacy. - Diuretics: risk of electrolyte shifts when combined with high amino acid intake. - Warfarin: monitor INR if large amounts of protein are introduced.

Frequently asked questions

What is Olimel Peri N4e used for?+
Olimel Peri N4e is an oral nutritional supplement that provides a balanced mix of essential and non‑essential amino acids. It is used to support patients with increased protein needs, such as those recovering from surgery, experiencing severe burns, or living with chronic kidney disease where dietary protein may be limited.
How does the amino acid blend in Olimel Peri N4e work?+
The blend supplies individual amino acids that are directly taken up by cells and incorporated into new proteins. By raising plasma amino acid levels, the product enhances nitrogen retention, promotes tissue repair, and supports the synthesis of enzymes and structural proteins needed for recovery and metabolic balance.
What is the usual dose of Olimel Peri N4e?+
The prescribed dose of Olimel Peri N4e is determined by the treating clinician based on the patient’s nutritional status, underlying condition, and overall protein requirements. Healthcare professionals tailor the regimen to achieve optimal amino acid supplementation without exceeding safe limits.
Is Olimel Peri N4e safe during pregnancy or breastfeeding?+
Safety data for Olimel Peri N4e in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under the guidance of a qualified healthcare provider.
How do I order Olimel Peri N4e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Olimel Peri N4e compare with other amino acid supplements?+
Olimel Peri N4e offers a comprehensive profile of ten amino acids, covering both essential and non‑essential types, which may provide broader metabolic support than formulations containing fewer components. Clinicians choose it when a full-spectrum amino acid replacement is desired for complex clinical situations.
What are the storage and handling requirements for Olimel Peri N4e?+
Store the product at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, excessive heat and direct sunlight to maintain stability and potency throughout its shelf life.
How is Olimel Peri N4e administered?+
Olimel Peri N4e is taken orally, usually dissolved in water or a suitable beverage as directed by the prescribing clinician. The exact administration schedule—such as frequency and timing relative to meals—should follow the healthcare professional’s instructions.
What are the most serious risks associated with Olimel Peri N4e?+
Serious adverse reactions, though rare, include allergic responses such as rash, swelling or anaphylaxis, as well as metabolic complications like hyperammonemia, metabolic acidosis, and significant electrolyte disturbances, particularly in patients with liver or kidney dysfunction.
Who should not use Olimel Peri N4e?+
Patients with known hypersensitivity to any of the listed amino acids, those with severe hepatic impairment at risk of hyperammonemia, and individuals with uncontrolled metabolic disorders should avoid this supplement unless a specialist determines it is safe.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Hellas
Origin
EU