GNH USA

Europe — EMA

Olimel N9e

GNH USA supplies Olimel N9e (Valine, Alanine, Arginine), a nutritional amino‑acid supplement for protein‑energy malnutrition and critical care.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9e, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel N9e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N9e provides amino acid supplementation that supports several metabolic and clinical conditions. - Protein‑energy malnutrition: helps restore nitrogen balance and promote lean body mass. - Post‑surgical recovery: assists in wound healing and tissue repair. - Chronic kidney disease (conservative management): supplies essential amino acids while limiting nitrogen load. - Inborn errors of metabolism: provides tailored amino acid profiles for specific enzymatic deficiencies. - Critical illness and intensive care: contributes to overall nutritional support when oral intake is insufficient.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions to amino‑acid mixtures are generally mild and related to gastrointestinal tolerance or hypersensitivity.

Common Side Effects: - Nausea: mild, transient upset stomach. - Diarrhea: loose stools, often resolves with continued use. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration in taste perception. - Headache: mild, unrelated to underlying condition. - Rash: mild skin erythema at the site of contact.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Hyperammonemia: elevated blood ammonia in patients with severe liver dysfunction. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe electrolyte imbalance: especially in patients with renal impairment. - Pulmonary edema: extremely rare, associated with fluid overload. - Hepatotoxicity: rare liver enzyme elevation.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Olimel N9e, clinicians should consider patient‑specific factors and monitor for potential complications. - Renal impairment: adjust dosage and monitor nitrogen waste products. - Hepatic dysfunction: watch for signs of hyperammonemia. - Pregnancy and lactation: evaluate risk‑benefit, use only if clearly needed. - Pediatric use: dose must be weight‑based and supervised by a specialist. - Concomitant nutrition therapy: avoid excessive total protein intake. - Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino‑acid mixtures can influence the absorption or metabolism of certain drugs and nutrients.

Major Interactions (Avoid): - Levothyroxine: amino acids may reduce oral absorption; separate administration by at least 4 hours. - Antiepileptic drugs (e.g., phenytoin): altered plasma protein binding may affect levels. - Iron supplements: chelation with amino acids can diminish iron absorption.

Moderate Interactions (Monitor Closely): - Antidiabetic agents: amino‑acid load may affect glucose control; monitor blood sugar. - Corticosteroids: increased protein catabolism may offset benefits; assess nutritional status. - Antibiotics (e.g., tetracycline): potential chelation; advise spacing of doses.

Frequently asked questions

What is Olimel N9e used for?+
Olimel N9e is an oral amino‑acid powder that provides essential and non‑essential amino acids to support protein synthesis, nitrogen balance and overall nutritional status in patients with protein‑energy malnutrition, post‑surgical recovery, chronic kidney disease, inborn errors of metabolism and other conditions requiring supplemental nutrition.
How does the active ingredient in Olimel N9e work?+
The formulation supplies individual amino acids that are absorbed in the gut and enter the bloodstream, where they act as building blocks for new proteins, serve as precursors for neurotransmitters and metabolic pathways, and help maintain nitrogen homeostasis, thereby supporting tissue repair and metabolic function.
What is the usual dose of Olimel N9e?+
The prescribed dose of Olimel N9e is determined by the treating clinician based on the patient’s age, weight, clinical condition and overall nutritional plan. Dosage adjustments may be needed for renal or hepatic impairment.
Is Olimel N9e safe during pregnancy or breastfeeding?+
Use of Olimel N9e in pregnancy or lactation should be considered only when clearly needed and after a risk‑benefit assessment by the prescriber. Limited data exist, so clinicians should monitor both mother and infant closely.
How do I order Olimel N9e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and import documentation.
How does Olimel N9e compare with other amino‑acid supplements?+
Olimel N9e offers a specific blend of ten amino acids, including both essential and condition‑specific non‑essential ones, providing a broader profile than many single‑amino‑acid products. This comprehensive mix can be advantageous for patients with complex metabolic needs, though selection should be guided by individual clinical requirements.
What are the storage and handling requirements for Olimel N9e?+
Store Olimel N9e below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Keep the container tightly closed to maintain powder stability and prevent contamination.
How is Olimel N9e administered?+
The powder is intended for oral use. It is typically reconstituted with water or a suitable liquid according to the prescriber’s instructions and taken with meals or as directed to optimize absorption.
What are the most serious risks associated with Olimel N9e?+
Serious risks, though rare, include anaphylactic reactions, hyperammonemia in patients with severe liver disease, metabolic acidosis, significant electrolyte disturbances, pulmonary edema from fluid overload, and hepatotoxicity. Immediate medical attention is required if any of these occur.
Who should not use Olimel N9e?+
Patients with known hypersensitivity to any of the listed amino acids, those with uncontrolled severe renal or hepatic failure, and individuals for whom a balanced protein intake cannot be safely managed should avoid using Olimel N9e unless a specialist determines it is appropriate.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter Czech Spol. S R.O.
Origin
EU