GNH USA

Europe — EMA

Olimel N9e

GNH USA supplies Olimel N9e (Amino Acid Mix), a nutritional supplement for protein‑energy wasting and malnutrition. Request a quote for global supply.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9e, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.

GNH USA supplies Olimel N9e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Olimel N9e provides amino acid supplementation for conditions where protein turnover is increased or intake is insufficient. - Post‑operative recovery: helps maintain nitrogen balance and supports tissue repair. - Chronic kidney disease: assists in managing protein‑energy wasting. - Severe malnutrition: contributes to rebuilding lean body mass. - Inherited metabolic disorders: supplies specific amino acids that may be deficient. - Critical illness (ICU): supports overall metabolic demand.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Amino acid mixtures are generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea: mild to moderate gastrointestinal discomfort. - Abdominal bloating: sensation of fullness or gas. - Diarrhoea: loose stools, usually transient. - Metallic taste: altered perception of taste. - Headache: mild tension‑type headache. - Mild hyperkalaemia: slight increase in serum potassium.

Serious or Rare Side Effects: - Severe hypersensitivity: rash, itching, swelling, or anaphylaxis. - Metabolic acidosis: significant pH imbalance in blood. - Hyperammonaemia: elevated ammonia levels causing neurological symptoms. - Renal impairment worsening: decline in kidney function beyond baseline. - Thromboembolic events: rare clot formation in veins or arteries.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When prescribing Olimel N9e, consider patient‑specific factors and monitor relevant clinical parameters. - Renal function: assess baseline creatinine and eGFR before initiation. - Hepatic function: evaluate liver enzymes in patients with liver disease. - Electrolyte balance: monitor serum potassium and sodium levels regularly. - Nutritional status: ensure the patient has a documented need for amino acid supplementation. - Concomitant nutrition therapy: coordinate with other enteral or parenteral formulas to avoid excess protein intake. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Amino acid preparations can influence the pharmacokinetics of certain drugs and vice versa.

Major Interactions (Avoid): - Levodopa: reduced absorption may diminish Parkinson's symptom control. - MAO inhibitors: risk of hypertensive crisis due to increased catecholamine precursors. - Thyroid hormone replacement: altered absorption leading to sub‑optimal dosing.

Moderate Interactions (Monitor Closely): - Anticoagulants (warfarin): potential change in INR values. - Antiepileptic drugs (phenytoin): possible displacement from protein binding sites. - Antibiotics (tetracyclines): chelation may reduce antibiotic efficacy.

Frequently asked questions

What is Olimel N9e used for?+
Olimel N9e is an oral amino acid powder that provides a balanced blend of essential and non‑essential amino acids. It is used to support patients with increased protein needs, such as those recovering from surgery, experiencing chronic kidney disease‑related wasting, or suffering from severe malnutrition.
How does the amino acid blend in Olimel N9e work?+
The amino acids act as direct substrates for protein synthesis and stimulate the mTOR pathway, which promotes muscle growth and nitrogen balance. They also participate in gluconeogenesis and other metabolic pathways that help maintain energy homeostasis during illness or recovery.
What is the usual dose of Olimel N9e?+
The prescribed dose of Olimel N9e is determined by the treating clinician based on the patient’s age, weight, clinical condition, and nutritional requirements. Healthcare professionals adjust the amount to meet individual protein‑energy goals.
Is Olimel N9e safe to use during pregnancy or breastfeeding?+
Safety data for Olimel N9e in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under strict medical supervision.
How do I order Olimel N9e from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Olimel N9e compare with other amino acid supplements?+
Olimel N9e offers a comprehensive profile of ten amino acids, covering both essential and non‑essential types, which may provide broader metabolic support than formulations containing fewer components. Clinicians choose it based on specific patient needs, tolerance, and the desired amino acid composition.
What are the storage and handling requirements for Olimel N9e?+
Store the powder at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, heat and direct sunlight to maintain stability and potency.
How is Olimel N9e administered?+
The powder is reconstituted with water or a suitable liquid according to the label instructions and taken orally. It can be mixed into enteral feeding formulas when required, following the prescribing clinician’s guidance.
What are the most serious risks associated with Olimel N9e?+
Serious risks include severe hypersensitivity reactions such as anaphylaxis, metabolic acidosis, hyperammonaemia, and worsening renal function. Patients should be monitored for any signs of these conditions, especially during the initial treatment period.
Who should not use Olimil N9e?+
Individuals with known hypersensitivity to any of the listed amino acids, those with uncontrolled hyperkalaemia, or patients with severe renal impairment where additional protein load is contraindicated should avoid using Olimel N9e.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Baxter B.V.
Origin
EU