Europe — EMA
Olimel N9e
GNH USA supplies Olimel N9e (Amino Acid Mix), a nutritional supplement for protein‑energy malnutrition and critical care. Request a quote for global supply.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9e, is a mixture of essential and non‑essential amino acids presented as a powder for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional supplementation.
GNH USA supplies Olimel N9e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N9e provides amino acid supplementation that supports several metabolic and clinical conditions. - Protein‑energy malnutrition: helps restore nitrogen balance and lean body mass. - Post‑surgical recovery: aids tissue repair and wound healing. - Chronic kidney disease (conservative management): supplies essential amino acids while limiting nitrogen load. - Inherited metabolic disorders (e.g., phenylketonuria): provides tailored amino acid composition to reduce harmful metabolites. - Critical illness and intensive care: contributes to overall nutritional support.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Amino acid mixtures are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild to moderate gastrointestinal discomfort. - Abdominal discomfort: bloating or cramping. - Diarrhea: loose stools, especially with rapid dose escalation. - Metallic taste: transient alteration in taste perception. - Headache: mild, often resolves with continued use.
Serious or Rare Side Effects: - Hyperammonemia: elevated blood ammonia levels, requiring monitoring. - Allergic reaction: rash, pruritus, or urticaria. - Metabolic acidosis: rare disturbance in acid‑base balance. - Renal impairment worsening: potential accumulation of nitrogenous waste. - Anaphylaxis: immediate hypersensitivity requiring emergency care.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When prescribing Olimel N9e, clinicians should consider several safety aspects. - Renal function assessment: evaluate baseline kidney performance before initiating therapy. - Hepatic function monitoring: check liver enzymes as amino acid metabolism occurs in the liver. - Electrolyte balance: monitor serum electrolytes, especially potassium and phosphate. - Gradual titration: increase dose slowly to minimise gastrointestinal upset. - Concomitant nutrition: coordinate with overall dietary plan to avoid excess protein intake. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Amino acid formulations can influence the pharmacokinetics of certain medicines.
Major Interactions (Avoid): - Levodopa: may reduce absorption of levodopa, diminishing its efficacy in Parkinson's disease. - Thyroid hormone replacement: can interfere with absorption of levothyroxine.
Moderate Interactions (Monitor Closely): - Anticonvulsants (e.g., valproate): may alter plasma amino acid levels.\n- Antibiotics (e.g., tetracycline): chelation may reduce antibiotic absorption. - Iron supplements: competition for intestinal transporters can lower iron uptake. - Diuretics: increased urinary loss of amino acids may require dose adjustment.