Europe — EMA
Olimel N9e
GNH USA supplies Olimel N9e (Amino Acid Mix), a nutritional supplement for protein‑energy malnutrition and critical care. Request a quote for global supply.
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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Olimel N9e, is a mixture of essential and non‑essential amino acids presented as a dietary supplement for oral use. It supports metabolic functions and protein synthesis in patients requiring nutritional support.
GNH USA supplies Olimel N9e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?
Olimel N9e provides amino acid supplementation that supports several clinical nutrition pathways.
- Protein‑energy malnutrition: helps restore nitrogen balance and lean body mass. - Post‑surgical recovery: aids tissue repair and wound healing. - Chronic kidney disease (conservative management): supplies essential amino acids while limiting nitrogen load. - Metabolic disorders affecting amino acid utilization: assists in maintaining adequate plasma amino acid levels. - Critical illness and intensive care: contributes to nutritional formulas for patients unable to meet needs orally.
What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
Amino acid mixtures are generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild gastrointestinal discomfort reported in some users. - Diarrhea: loose stools may appear during initial supplementation. - Abdominal bloating: transient feeling of fullness or gas. - Metallic taste: occasional alteration in taste perception. - Headache: mild headache reported occasionally. - Skin redness at oral mucosa: mild irritation in rare cases.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or anaphylaxis in hypersensitive individuals. - Hyperammonemia: elevated ammonia levels in patients with severe liver dysfunction. - Metabolic acidosis: rare disturbance of acid‑base balance. - Severe gastrointestinal distress: persistent vomiting or severe abdominal pain. - Renal impairment exacerbation: worsening kidney function in susceptible patients. - Unexplained hypotension: low blood pressure not attributable to other causes.
What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?
When prescribing Olimel N9e, clinicians should consider several safety aspects.
- Renal function: assess kidney performance before initiating therapy. - Liver health: monitor hepatic parameters in patients with existing liver disease. - Pregnancy & lactation: evaluate risk‑benefit ratio; use only if clearly needed. - Drug interactions: review concomitant medications that affect amino acid metabolism. - Age considerations: adjust monitoring for pediatric or geriatric patients. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.
What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?
Amino acid supplements can influence the pharmacokinetics of certain drugs.
Major Interactions (Avoid): - Levodopa: may compete for intestinal transport, reducing absorption. - Anticonvulsants (e.g., valproate): can alter plasma amino acid levels, affecting efficacy.
Moderate Interactions (Monitor Closely): - Thyroid hormones: high amino acid load may modify hormone binding. - Insulin and oral hypoglycemics: amino acids can affect glucose metabolism, requiring dose adjustments. - Certain antibiotics (e.g., tetracyclines): may chelate with calcium‑containing formulations, reducing absorption. - Warfarin: protein intake changes can influence INR stability. - Diuretics: increased nitrogen excretion may affect fluid‑electrolyte balance.